[Significance of blood ribose measurement by gas liquid chromatography in ischemic hear disease].

A method for measuring serum ribose by gas liquid chromatography is described, prolonging the sample stability and simplifying its storage. Serum ribose content is decreased in patients with angina of effort (functional class III).

Effect of disaggregation on calpain activity in explants from rat thyroid glands.

We studied the regulation of calpains in explants from rat thyroid glands. Collagenase disaggregation decreased proteinase activity in thyrocytes. It was hypothesized that this effect is mediated by heterotrimeric G proteins, protein kinase C, and tyrosine kinase, but not via Ca(2+) and cAMP-dependent signal pathway.

Intracellular distribution and regulation of calpains in the thyroid gland.

We studied the distribution of calpains in various subcellular thyrocyte fractions and evaluated the possibility for direct activation of calpain localized in the plasma membrane by thyrotropin. Direct activation of calpain bound to the plasma membrane did not underlie transduction of the thyrotropin signal to Ca(2+)-dependent proteinases.