Chemical Composition and Toxicity of PM and PM Samples near Open-Pit Mines and Coal Power Stations.

Particulate matter (PM) <10 μm in size represents an extremely heterogeneous and variable group of objects that can penetrate the human respiratory tract. The present study aimed to isolate samples of coarse and ultrafine PM at some distance from polluting industries (1−1.5 km from the border of open-cast mines).

Investigation of the genotoxic effects of fluoride on a bone tissue model.

Fluorides are thought to be a major cause of osteocarcinogenesis, due to their widespread industrial use, ability to accumulate in bone tissue, and genotoxic and probable carcinogenic properties. In vitro experiments investigating the genotoxic potential of fluorides in bone tissue models can provide valuable indirect information on their involvement in osteocarcinogenesis. Here, we investigated whether sodium fluoride (NaF) has the ability to induce DNA damage and chromosomal abnormalities in human osteosarcoma cells after 48 and 72 h of exposure.