Publications by authors named "E A SAPIO"
Article Synopsis
- Alzheimer's disease is linked to abnormal deposits of beta-amyloid and tau proteins, and blood biomarkers may help detect them; decreased kidney function could impact how these biomarkers are cleared from the body.
- This study analyzed the relationship between kidney function, blood biomarker levels, and cognitive impairment in Alzheimer’s patients without chronic kidney disease, using retrospective data and blood samples to measure various protein levels.
- Results showed that only plasma levels of Aβ42 were significantly affected by kidney function, suggesting that renal function influences the clearance of this particular protein, while other Alzheimer's biomarkers remained unaffected.
Article Synopsis
- Headache disorders like migraine and tension-type headaches are often underdiagnosed and undertreated, despite advancements in targeted medications; NSAIDs and analgesics are still the most commonly used treatments.
- A study conducted in 2022 at a tertiary headache center tracked 283 migraine patients, revealing that NSAID use decreased over three months while triptan use increased, indicating a shift in treatment strategies.
- Results showed that adding prophylactic therapies like topiramate or amitriptyline was linked to reduced NSAID intake and headache frequency, highlighting the need for tailored treatment plans in managing headaches effectively.
We describe the entire process leading to the start-up of a hematopoietic stem cell transplantation center at the Hiwa Cancer Hospital, in the city of Sulaymaniyah, Kurdistan Iraqi Region. This capacity building project was funded by the Italian Development Cooperation Agency and implemented with the support of the volunteer work of Italian professionals, either physicians, nurses, biologists and technicians. The intervention started in April 2016, was based exclusively on training and coaching on site, that represent a significant innovative approach, and led to a first autologous transplant in June 2016 and to the first allogeneic transplant in October.
View Article and Find Full Text PDFThe experimental dosimetry of 2 radiotherapy beams produced by a 60Co Picker unit and by a Siemens 4 MV unit, respectively, was analyzed to verify the use of tissue air ratio (TAR) and tissue maximum ratio (TMR) in the computerized planning of total body irradiation (TBI). The use of a small ionization chamber PRO5P Capintec in anthropometric phantoms allowed us to test a computed calculation procedure adopted to reduce both experimental uncertainties and time consumption. The experimental test on the computed procedure was also useful to identify the equivalent fields the patient's body had to be divided into for dosimetric planning.
View Article and Find Full Text PDFA numerical method for the reconstruction of bremsstrahlung spectra has been applied to the analysis of simulated data. The method is found to be reliable in reconstructing x-ray spectra of maximum energy up to 10 MeV. Measurements of aluminum transmission data carried out for five linear accelerators have also been analyzed by this method to determine the fractional energy fluence.
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