[Treatment of infectious complications of experimental acute radiation injury with combined antibiotic sulacillin].

An anti-infectious effect of sulacillin (ampicillin/sulbactam) is higher than that of ampicillin in treatment of irradiated mice infected with a beta-lactamaseproducing strain of Kl. pneumoniae. Involving of sulacillin as a principal antibiotic into the therapeutic scheme for acute radiation sickness results in 67% dogs survival at LD90/45.

[Advances and prospects of a combined therapy of acute radiation injury in experiments].

We present the results of a long-standing experimental development of ways and means for acute radiation sickness treatment that have been authorized for application in medicine and are mostly aimed at large-scale accidental injuries. The paper describes means for early treatment (prodigiosan, desoxynate, typhoid vaccine, proteus vaccine), a myeolopoiesis stimulant (estradiol dipropionate), a detoxication procedure (hemosorption), substitution therapy with bone marrow cells and peripheral blood mononuclears, anti-infectious schemes comprising antibiotics and polyvitamins.