Effect of vitamin C supplementation on some leukocyte parameters in American mink (Neovison vison) with abnormal granulogenesis.

Sapphire mink, a mutant colour variant of American mink, is an animal model of the Chediak-Higashi syndrome (CHS). As in CHS, there are enlarged cytoplasmic granules in various cell types including leukocytes in Sapphire mink due to abnormal granulogenesis. Such cellular abnormality leads to a weakening of the immune defence as a consequence to the development of infections.

[Effects of clinical indices and anti-angina therapy on the quality of life in patients with stable angina pectoris].

Aim: To determine effects of basic clinical indices and various antianginal drugs on quality of life (QL) assessed with general and special questionnaire before and after selection of antianginal therapy in patients with stable angina pectoris.

Material And Methods: The study enrolled 89 patients with stable angina (functional class II-IV). They were examined before and after decision on adequate therapy.