[ANTHELMINTIC SUBSTANCES: MAIN CLASSES, PROBLEMS, TRENDS IN DEVELOPMENT AND PROSPECTS].

The review chronologically considers the main classes of the currently available anthelminthic substances: early anthelmintic compounds, benzimidazoles, imidazolthiazoles, tetrahydropyrimidines, avermectins and milbemycins, and salicylanilides. Great attention is paid to novel substances (emodepside, monepantel, derquantel, tribendimidine) and promising developments. Some aspects of the molecular mechanisms of action of anthelmintics, their resistance, and alternative dehelmintization methods are discussed.

[EXTERNAL QUALITY ASSESSMENT FOR THE LABORATORY IDENTIFICATION OF THE PATHOGENS OF PARASITIC DISEASES AS AN ELEMENT FOR IMPROVING THE POSTGRADUATE TRAINING OF SPECIALISTS].

Within the framework of the Federal External Quality Assessment (EQA) System and in the context of postgraduate training improvement for health workers in 2010-2014, specialists from the laboratories of the therapeutic-prophylactic organizations and institutions of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare were examined for their professional competence in microscopically identifying the pathogens of parasitic diseases in feces. The virtual remote educational computer technology tools that included different combinations of 16 helminthic species, 5 intestinal protozoan species, and a number of artefacts, were used. The specialists from 984 laboratories of multidisciplinary therapeutic-prophylactic organizations and hygiene and epidemiology centers in all Federal Districts of the Russian Federation were covered.

[A PROJECT TARGETED APPROACH TO IMPROVING THE ENVIRONMENTAL TRAINING OF PARASITOLOGISTS].

A project targeted approach is the methodological basis for organizing professional education, which deals with learning objectives, content, and technologies as a professional activity design where all components-of a teaching process are constructed on an integrative basis. The project targeted approach is the basis for a project method. The latter ensures that the learning objectives are achieved through the creation of a professionally significant problem, which should yield a real, tangible practical result.

[THE EPIDEMIOLOGICAL AND EPIZOOTIOLOGICAL COMPONENT OF TOXOCARIASIS FOCI AS AN ELEMENT OF THE ENVIRONMENTAL MANAGEMENT SYSTEM (IN CASE OF THE REPUBLIC OF ALTAI)].

The epidemiological and epizootiological features of toxocariasis foci were investigated in the Republic of Altai. The results of coproovoscopic examinations of dogs, those of serological screening for toxocariasis among different age and occupational groups and coniingents at risk for HIV infection, hepatitis B and C, patients with allergic and bronchopulmonary diseases, toxocariasis mortality rates in the Republic of Altai, and the materials of sanitary and parasitological studies of soil and other environmental constituents for Toxocara canis eggs provide support for the poor situation of toxocariasis in the region. Relying on the current standards and the findings of this study, the Republic of Altai may be referred to as a moderately dangerous area at medium risk for contamination in terms of epidemic, epizootic, and environmental hazards.