Publications by authors named "E A Opiyo"

Article Synopsis
  • A mental health study in western Kenya tested the feasibility of delivering treatments for major depression and PTSD through non-specialist staff in primary care settings, incorporating both in-person and mobile health (mHealth) options due to the COVID-19 pandemic.
  • The chosen intervention involved either psychotherapy (Interpersonal Psychotherapy) or medication (fluoxetine), with 2,162 public sector primary care patients participating.
  • A secondary analysis assessed participants' preferences for mHealth or in-person treatment, exploring their reasons for choosing one method over the other and comparing demographic and clinical characteristics between the two groups.
View Article and Find Full Text PDF

Malaria remains the leading cause of hospitalization and death in the healthcare system. This study explored the malaria burden and community response to government malaria control programs in Omoro district. This retrospective study involved 576 patient results from purposely selected health facilities data from health center III (HCIII) of Odek, Bobi, and Lapainat and health center IV (HCIV) of Lalogi.

View Article and Find Full Text PDF

SMART DAPPER is an implementation science study responding to mental health treatment gaps for depression and trauma-related disorders in Sub-Saharan Africa (SSA). We report on patient experiences in a study using a Sequential, Multiple Assignment Randomized Trial (SMART) design to test first and second line non-specialist treatment using psychotherapy (Interpersonal Psychotherapy [IPT] or medication (fluoxetine [FLX]), integrated within public sector primary care in western Kenya. An embedded qualitative study conducted in-depth interviews (n = 17) and three (n = 3) focus group discussions with participants (May to October 2021).

View Article and Find Full Text PDF

Background: Scalable PTSD screening strategies must be brief, accurate and capable of administration by a non-specialized workforce.

Methods: We used PTSD as determined by the structured clinical interview as our gold standard and considered predictors sets of (a) Posttraumatic Stress Checklist-5 (PCL-5), (b) Primary Care PTSD Screen for the DSM-5 (PC-PTSD) and, (c) PCL-5 and PC-PTSD questions to identify the optimal items for PTSD screening for public sector settings in Kenya. A logistic regression model using LASSO was fit by minimizing the average squared error in the validation data.

View Article and Find Full Text PDF

Background: Malaria remains one of the most critical disease causing morbidity and mortality in Uganda. Indoor residual spraying (IRS) and the use of insecticide-treated bed nets are currently the predominant malaria vector control interventions. However, the emergence and spread of insecticide resistance among malaria vectors threaten the continued effectiveness of these interventions to control the disease, particularly in high transmission areas.

View Article and Find Full Text PDF