Publications by authors named "E A Marsden"

Aims: Previous neuroimaging research in alcohol use disorder (AUD) has found altered functional connectivity in the brain's salience, default mode, and central executive (CEN) networks (i.e. the triple network model), though their specific associations with AUD severity and heavy drinking remains unclear.

View Article and Find Full Text PDF

In this work, we demonstrate the training, conversion, and implementation flow of an FPGA-based bin-ratio ensemble spiking neural network applied for radioisotope identification. The combination of techniques including learned step quantisation (LSQ) and pruning facilitated the implementation by compressing the network's parameters down to 30% yet retaining the accuracy of 97.04% with an accuracy loss of less than 1%.

View Article and Find Full Text PDF

Alcohol use disorder is associated with overvaluation of alcohol relative to other rewards, in part due to dynamic increases in value in response to alcohol-related cues. In a neuroeconomic framework, alcohol cues increase behavioral economic demand for alcohol, but the neural correlates these cue effects are unknown. This functional magnetic resonance imaging study combined a neuroeconomic alcohol purchase task with an alcohol cue exposure in 72 heavy drinkers with established sensitivity to alcohol cues (51 % female; mean age=33.

View Article and Find Full Text PDF

The cavity inside fullerene C provides a highly symmetric and inert environment for housing atoms and small molecules. Here we report the encapsulation of formaldehyde inside C by molecular surgery, yielding the supermolecular complex CHO@C, despite the 4.4 Å van der Waals length of CHO exceeding the 3.

View Article and Find Full Text PDF

Single-atom dynamics of noble-gas elements have been investigated using time-resolved transmission electron microscopy (TEM), with direct observation providing for a deeper understanding of chemical bonding, reactivity, and states of matter at the nanoscale. We report on a nanoscale system consisting of endohedral fullerenes encapsulated within single-walled carbon nanotubes ((Kr@C)@SWCNT), capable of the delivery and release of krypton atoms on-demand, via coalescence of host fullerene cages under the action of the electron beam () or heat (). The state and dynamics of Kr atoms were investigated by energy dispersive X-ray spectroscopy (EDS), electron energy loss spectroscopy (EELS), and X-ray photoelectron spectroscopy (XPS).

View Article and Find Full Text PDF