Publications by authors named "E A M Holman"
MED-EL Bonebridge implantation in pediatric patients age 11 Years and younger: Is it safe and effective?
Int J Pediatr Otorhinolaryngol
December 2024
Objective: To present our experience with off-label MED-EL Bonebridge implantation in pediatric patients younger than 12 years of age and compare outcomes to pediatric patients 12 years and older.
Methods: Pediatric patients who underwent Bonebridge implantation were included in a retrospective cohort study and were categorized by off-label use (<12 years) and ≥12 years at time of bone conduction implantation (BCI). Hearing outcomes were collected after implant activation, which was typically 4-8 weeks post-implantation.
Colorectal cancer encompasses a heterogeneous group of malignancies that differ in pathophysiological mechanisms, immune response and infiltration, therapeutic response, and clinical prognosis. Numerous studies have highlighted the clinical relevance of tumor-infiltrating immune cells among different types of colorectal tumors yet vary in cell type definitions and cell identification strategies. The distinction of immune signatures is particularly challenging when several immune subtypes are involved but crucial to identify novel intercellular mechanisms within the tumor microenvironment.
View Article and Find Full Text PDFObjective: We examined whether perceived trust in media was associated with post-Hurricane Harvey traumatic stress symptoms and tested whether it buffered the association between hurricane-related media exposure and post-Hurricane Harvey traumatic stress symptoms.
Method: A probability-based, representative sample of Texas residents, drawn from the GfK KnowledgePanel, were surveyed online three times: 2 weeks ( = 1,137), 6 weeks ( = 1,023), and 14 months ( = 748) after Hurricane Harvey (a Category 4 storm) made landfall in 2017. Measures included traumatic stress symptoms, Hurricane Harvey-related media exposure, perceived trust in that media, Hurricane Harvey exposures, and demographics.
Article Synopsis
- The utility of spatial omics for precision medicine is limited by challenges in linking disease states to cellular patterns.
- This study employs a spatial context-dependent method to analyze existing ulcerative colitis patient data, revealing complex structures and rare cell types in colonic biopsies.
- The findings enhance our understanding of disease mechanisms and propose a strategy for automating the detection of intricate cellular architectures in spatial biology data, aiding in diagnosis and treatment.
Introduction: After the United States Medical Licensing Examination (USMLE) shifted the Step 1 licensure exam to pass/fail, there have been limited studies to analyze changes in student study strategies.
Material And Methods: Surveys were distributed to third- and fourth-year medical students at the University of Michigan Medical School (UMMS). The response rate was 66%.