Publications by authors named "E A Lyashenko"
Article Synopsis
- The study investigates the toxicity risks of titanium dioxide (TiO) and zirconium dioxide (ZrO) nanoparticles, which are widely used in various industries.
- Pregnant rats were used in experiments to test the effects of these nanoparticles on maternal health and the development of their offspring, with a dosage of 100 mg/kg/day.
- The results indicate that while neither TiO nor ZrO nanoparticles exhibited embryonic or teratogenic effects on the fetus, they did influence postnatal development in the offspring.
Induced pluripotent stem cell (iPSC) derived cell types are increasingly employed as in vitro model systems for drug discovery. For these studies to be meaningful, it is important to understand the reproducibility of the iPSC-derived cultures and their similarity to equivalent endogenous cell types. Single-cell and single-nucleus RNA sequencing (RNA-seq) are useful to gain such understanding, but they are expensive and time consuming, while bulk RNA-seq data can be generated quicker and at lower cost.
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- New studies show that understanding how people think and feel is super important for helping with mental health diagnoses and treatments.
- Researchers from 12 countries looked at how a person's nationality affects their social thinking skills, finding that where someone is from can really matter.
- The results suggest we need to change how we study and help people with social thinking abilities to make sure it works for everyone, no matter where they live.
[The role of the gut microbiota in Parkinson's disease].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2021
Recently, an important role in the development of Parkinson's disease (PD) is assigned to the gastrointestinal tract and the enteral nervous system. In particular, the pathological process of PD begins in the gastrointestinal tract decades before progressing to the central nervous system. The microbiota-gut-brain axis is a two-way connecting system between the central nervous system and the gastrointestinal tract.
View Article and Find Full Text PDF[Neuroendocrine and metabolic impairments in patients with Parkinson's disease].
Zh Nevrol Psikhiatr Im S S Korsakova
November 2020
Neuroendocrine and neurometabolic disorders, although occasionally noted in Parkinson's disease (PD), existed in the shadow of motor and non-motor symptoms (hypokinesia, rigidity, tremor, depression, constipation, etc.). In recent years, they are increasingly being diagnosed and are the subject of special research.
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