[Lipid metabolism characteristics in disabled persons as a consequence of cerebrovascular diseases].

Lipid metabolism condition in young, mature (till 35 y.o) and elderly disabled persons as a consequence of cerebral diseases has been investigated. It was established that all three groups differ in clinical presentation and various kinds of lipid metabolism abnormalities.

[Proteolytic processes in lung tissue of rat posterity after whole-body chronic irradiation with low doses].

Intensification of proteolytic processes accompanied by inhibited antiprotease activity in lung tissue of first generation posterity of rats irradiated with a total dose of 0.25 Gy (0.01 Gy per day) before gestation was shown.

[Proteolytic system in lungs upon inhalation exposure to low doses of lead salts].

Changes in proteinase--antiproteinase activities in lungs as a result of short-term (for 1 week) inhalation of rats with 0.01% (CH3COO)2 Pb have wholly compensative patterns, but it have been found increased cathepsine B activity as a negative prognostic factor. Chronic (for 2 month) toxicant inhalation caused considerable activation of both trypsine and cathepsine B under decreasing alpha 1-antitrypsine and alpha 2-macroglobuline activities.

[The biological effects of combined exposure to low-dose irradiation and heavy metal ions].

It was shown that chronic 0.25 Gy irradiation of rats (0.01 Gy/day) at background of heavy metal penetration (Cu2+, 20 mg/l or Co2+, 5 mg/l) with drinking water had caused significant accumulation of the free-radical products proportional to exhausting antioxidant and oxidizing-reduction potential in various organs and tissues.

[Lipid peroxidation in the lungs upon inhalation exposure to low concentrations of lead salts].

Effects of inhalation with low concentration lead salts on lipid peroxidation intensity and antioxidative system state were investigated in respiratory pulmonary branch in rats after both short-term and chronic exposures to 0.01% Pb(CH3COO)2. It was shown that the short-term toxic action had considerably affected on the antioxidant system state in lungs as a result of tissue antioxidative activity exhausting.