Biomimetic Materials Based on Poly-3-hydroxybutyrate and Chlorophyll Derivatives.

Electrospinning of biomimetic materials is of particular interest due to the possibility of producing flexible layers with highly developed surfaces from a wide range of polymers. Additionally, electrospinning is characterized by a high simplicity of implementation and the ability to modify the produced fibrous materials, which resemble structures found in living organisms. This study explores new electrospun materials based on polyhydroxyalkanoates, specifically poly-3-hydroxybutyrate, modified with chlorophyll derivatives.

Creation of a Biobank of the Sperm of the Honey Bee Drones of Different Subspecies of L.

The cryopreservation of gametes and embryos is an important element of biodiversity conservation. One species in need of conservation is the honey bee L. Changing environmental factors, especially the anthropogenic factor, have led to a reduction in the numbers of this insect species.

Effect of substituents in chlorin e derivatives on the loading efficiency of the photosensitizer into the liposome membrane and their biological activity.

In this work, we incorporated the hydrophobic alkylamide and hydroxyalkylamide derivatives of chlorin e into the lipid bilayer of liposomes. We obtained the data on the effectiveness of incorporation of studied compounds and have determined the size of liposomes and their stability when stored in liquid form. We also investigated the bioactivity of chlorin photosensitizers and compared the photodynamic activity of studied compounds in free and liposomal forms.

Synthesis of amide derivatives of chlorin e6 and investigation of their biological activity.

In this work there is a synthesis of new photosensitizers which is based on amide derivatives of chlorin е6 . For the disclosure of an extra ring of the initial compound - pheophorbide a 1, we used primary aliphatic amines with 4-12 carbon atoms in the alkyl chain. The reaction is carried out under mild conditions in chloroform with heating to 40 ºС.

[Tactics of management of preschool children with different variants of speech delay].

Objective: To study the efficacy of neurometabolic treatment in dependence of different variants of speech delay (SD), general underdevelopment of speech (GUDS) type, in preschool children.

Material And Methods: The study included 130 children, aged 4-6 years, with SD, GUDS type, Most of children were boys (74%). Clinical and psychological characteristics and efficacy of neurorehabilitation were studied in 3 parallel groups.