[Astrobiological investigations on board Russian space crafts].

The possibility of prebiotic synthesis of nucleic acids components (nucleotides) has been demonstrated under condition of the space orbital stations and satellites under effect of all space radiation spectra. Since a lot of different nucleic acids components are known to be present within small space bodies, we have to investigate their chemical complication in respect with such components as nucleotides. The goal of this work is to review our results in the field of prebiotic synthesis of purine and pyrimidine nucleotides on the board of Russian space crafts.

Exobiological investigations on Russian spacecrafts.

To investigate the possibility of prebiotic synthesis of organic molecules in open space, conditions involved irradiating nucleosides and inorganic phosphate during five Earth-orbiting Russian space missions that included Salut-7 (13- and 16-month missions), Mir, Bion-11, and Cosmos-2044. Dry films of samples were exposed from 2 weeks up to 16 months to the entire set of factors encountered in open space during Earth-orbiting missions. After each mission, products synthesized during flight and any compounds that remained undegraded were analyzed.

Prebiotic synthesis of nucleotides at the Earth orbit in presence of Lunar soil.

Modern studies now favor the fact that extraterrestrial organic molecules served as an important source of biological important substances on the primitive Earth. It is presumed that these space-made organic molecules could be transported safely to the Earth surface being associated with mineral grains. It is important to test whether nucleotides synthesized in Earth orbit could be protected by lunar surface regolite.

Study of the peptide prebiotic synthesis in context of exobiological investigations on earth orbit.

Dry films of amino acids mixtures glycine+ tryptophan and tryptophan were exposed on the surface of "Mir" station. Similar films were irradiated by vacuum ultra violet (145 nm) and ultra violet (254 nm) in the laboratory experiments. Gly-Gly, Trp-Gly, Gly-Trp, Tpr-Trp and Trp-Trp-Trp were the main reaction products for the experimental mixture glycine + tryptophan and Tpr-Trp and Trp-Trp-Trp for tryptophan.