Publications by authors named "E A Kornilov"

: Decreased cerebral oximetry (rSO) in cardiac surgery is associated with postoperative delirium (POD). However, interventions optimizing intraoperative rSO are inconclusive. : In this prospective observational cohort study, the relationship between rSO, middle cerebral artery blood flow velocity (MCAV), and processed EEG was assessed in cardiac surgery patients with and without POD.

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Background: Cardiac surgery involving cardiopulmonary bypass induces a significant systemic inflammatory response, contributing to various postoperative complications, including pulmonary dysfunction, myocardial and kidney injuries.

Objective: To investigate the effect of Nitric Oxide delivery via the cardiopulmonary bypass circuit on various postoperative outcomes.

Design: A prospective, single-centre, double-blinded, randomised controlled trial.

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Article Synopsis
  • People with COVID-19 who need special breathing support called ECMO often have problems related to their brain's blood flow regulation.
  • A study looked at 48 patients, some with COVID-19 and some without, to see how their brains were affected.
  • It was found that patients with COVID-19 had more trouble with brain blood flow regulation compared to those without the virus.
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Article Synopsis
  • The study explores a new anesthesia method using ketamine-induced conscious sedation during deep brain stimulation (DBS) surgery for Parkinson's patients, aiming to improve patient experience while maintaining safety and surgical effectiveness.
  • Patients were randomly assigned to receive either ketamine or saline during the physiological testing phase, with both groups receiving moderate sedation before and after.
  • Results showed that ketamine provided similar quality of microelectrode recordings and lead localization compared to the traditional awake method, while significantly enhancing patient satisfaction without negative impacts on health or cognitive function.
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: Early postoperative mobilization is central for postoperative outcomes after lower extremity joint replacement surgery. By providing adequate pain control, regional anaesthesia plays an important role for postoperative mobilization. It was the objective of this study to investigate the use of the nociception level index (NOL) to determine the effect of regional anaesthesia in hip or knee arthroplasty patients undergoing general anaesthesia with additional peripheral nerve block.

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