[The importance of the vertical transmission of enteroviruses in the epidemiology of congenital viral infections].

A total of 814 newborns were examined using a highly sensitive method of indication of viral antigens. A high incidence of congenital viral infection was revealed: 450 per 1000 live-born children. Enteroviral infections (mainly Coxsackie) ranked first in prevalence.

[An experimental model of the vertical transmission of the Coxsackie-group enteroviruses and its use in developing methods to prevent congenital coxsackievirus infection].

An experimental model of vertical transmission of Coxsackie group enteroviruses was developed in BALB/c mice the first generation of which was infected with Coxsackie A18 virus in the neonatal period. Persistence of the virus was demonstrated in all females of the first generation tested and in 90.9% to 100% of the animals of the next two generations.

[The role of prenatal Coxsackievirus infection in the etiology of congenital heart defects in children].

Sixty-two children with congenital heart diseases and 100 normal children were examined, their age ranging from 5 days to 6 years. Indicators of intrauterine enterovirus infection risk were detected in 93.5% of children with congenital heart diseases and in just 21.