Publications by authors named "E A Islam"

Neisseria gonorrhoeae, which causes the sexually transmitted infection gonorrhea and Neisseria meningitidis, a leading cause of bacterial meningitis and septicemia, are closely related human-restricted pathogens that inhabit distinct primary mucosal niches. While successful vaccines against invasive meningococcal disease have been available for decades, the rapid rise in antibiotic resistance has led to an urgent need to develop an effective gonococcal vaccine. Several surface antigens are shared among these two pathogens, making cross-species protection an exciting prospect.

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Neisseria gonorrhoeae is an on-going public health problem due in part to the lack of success with efforts to develop an efficacious vaccine to prevent this sexually transmitted infection. The gonococcal transferrin binding protein B (TbpB) is an attractive candidate vaccine antigen. However, it exhibits high levels of antigenic variability, posing a significant obstacle in evoking a broadly protective immune response.

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Background: Lower urinary tract symptoms (LUTS) adversely affect the quality of life and are usually under-reported because of a stigma associated with these symptoms. Unless specifically probed for these symptoms, most patients do not report Lower urinary tract symptoms. This study focused on the treatment-seeking behaviour of otherwise healthy individuals who had LUTS.

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Floating treatment wetlands (FTWs) consist of buoyant rafts that support the growth of macrophytes on waterbodies. The long-term performance of these rafts depends on their buoyancy and resistance to weathering. Here, we present a protocol for establishing low-cost FTWs for large-scale wastewater reclamation by integrating traditional ecological knowledge with modern engineering principles.

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Article Synopsis
  • Epidemiological studies indicate that the 4CMenB (Bexsero) vaccine might offer some protection against Neisseria gonorrhoeae, which is related to the meningococcal bacteria.
  • Research in mice shows that while Bexsero triggers a strong immune response, it does not protect everyone, prompting a deeper investigation into the immune mechanisms involved.
  • The study reveals that Bexsero vaccination leads to a significant immune response, involving various antibody levels and T cell subsets, potentially identifying factors that contribute to immune protection against gonorrheal infections.
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