[Jejunum intersticium in mongolian gerbils after the flight on spacecraft Foton-M3].

Methods of light optical microscopy were used to explore histoarchitectonics, topography and tinctorial properties of the extracellular phase of fibers of jejunum wall intersticium in Mongolian gerbils following 12-day orbital flight aboard Foton-M3, ground-based simulation of the spaceflight factors in the KONTUR-L facility, and in the group of biological control Postflight destructive changes were found in reticulin fibers (type-III collagen) of villi stroma, intercrypt intersticium and submucosa. Local acidophilia and fiber homogenization formed in type I collagen present in the intestinal subserous layer, muscular layers endomysium and submucose against the background of progressing edema and arterial, venous plethora and lymphostasis. Elastic component of the intersticium was disarranged in the structures of internal elastic membrane of submucous vessels, fragmented and partly reduced.

[Tissue-specific reaction of the mucous coat of herbals' small gut under the influence of spaceflight factors on board biosat "Foton M3"].

Methods of light-optical microscopy, morpho- and cytometry and histochemisty were used to study the epithelial lining of herbal's small gut after 12-day flight in biosat "Foton M3". Changes in mucous coat histoarchitectonics included branching of villi and cystic lumps lined with prismatic epithelium. Shortening of the mucous membrane villi was accompanied by reduction of prismatic epithelium height, increase in the number of goblet cells and change of their dislocation, stimulation of excretion of biosynthesis products on the brush border surface pointing to impairment of the interstitial barrier function.

[Rna content of gerbil hepatocytes after the flight aboard space platform Foton-M3].

The paper compares and contrasts the results of measuring the hepatocyte cytoplasm area and RNA content in 35 gerbils in three series of experiments, i.e. the vivarium control, modeled space flight (synchronous control) and exposure to the factors of 12-d Foton-M3 orbital flight.

[Morphofunctional state of hepatocytes nuclear apparatus in Mongolian herbils after the flight on space apparatus Foton-M3].

Morphofunctional state of hepatocytes nuclear apparatus was analyzed in the liver of Mongolian gerbils Meriones unguiculatus returned from 12-d space flight of Foton-M3 (SF) and their vivarium and ground synchronous controls. Volume, ploidy and number of hepatocyte nuclei, nucleolus dimensions and number as well as contacts with karyolemma were determined in the central, intermediate and peripheral areas of the liver classical lobe. Also, total number of mitoses and amitoses was determined in the liver parenchyma.