RLC resonator with diode nonlinearity: Bifurcation comparison of numerical predictions and circuit measurements.

A nonlinear RLC resonator is investigated experimentally and numerically using bifurcation analysis. The nonlinearity is due to the parallel combination of a semiconductor rectifier diode and a fixed capacitor. The diode's junction capacitance, diffusion capacitance, and DC current-voltage relation each contribute to the nonlinearity.

Emergence of multistability and strongly asymmetric collective modes in two quorum sensing coupled identical ring oscillators.

The simplest ring oscillator is made from three strongly nonlinear elements repressing each other unidirectionally, resulting in the emergence of a limit cycle. A popular implementation of this scheme uses repressor genes in bacteria, creating the synthetic genetic oscillator known as the Repressilator. We consider the main collective modes produced when two identical Repressilators are mean-field-coupled via the quorum-sensing mechanism.

Transitions between phases of genomic differentiation during stick-insect speciation.

Speciation can involve a transition from a few genetic loci that are resistant to gene flow to genome-wide differentiation. However, only limited data exist concerning this transition and the factors promoting it. Here, we study phases of speciation using data from >100 populations of 11 species of Timema stick insects.

Flexible dynamics of two quorum-sensing coupled repressilators.

Genetic oscillators play important roles in cell life regulation. The regulatory efficiency usually depends strongly on the emergence of stable collective dynamic modes, which requires designing the interactions between genetic networks. We investigate the dynamics of two identical synthetic genetic repressilators coupled by an additional plasmid which implements quorum sensing (QS) in each network thereby supporting global coupling.

Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis.

The cilium both releases and binds to extracellular vesicles (EVs). EVs may be used by cells as a form of intercellular communication and mediate a broad range of physiological and pathological processes. The mammalian polycystins (PCs) localize to cilia, as well as to urinary EVs released from renal epithelial cells.