Publications by authors named "E A Goytizolo"

Article Synopsis
  • * A study analyzed nearly 50,000 patients and found only a 0.1% rate of allergic reactions in rPCNA patients who received cefazolin, indicating it's generally safe for this group.
  • * No significant differences were observed in infection rates (superficial, deep, or C. difficile) between rPCNA patients receiving cefazolin and those using alternative antibiotics, suggesting cefazolin is a safe choice.
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Background: Optimal analgesic protocols for total knee arthroplasty (TKA) patients remain controversial. Multimodal analgesia is advocated, often including peripheral nerve blocks and/or periarticular injections (PAIs). If 2 blocks (adductor canal block [ACB] plus infiltration between the popliteal artery and capsule of the knee [IPACK]) are used, also performing PAI may not be necessary.

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Article Synopsis
  • Duloxetine can reduce opioid consumption after total knee arthroplasty without increasing pain levels.
  • In a study with 160 patients, those taking duloxetine consumed significantly less opioid medication compared to those on placebo.
  • The results suggest that duloxetine may provide an effective alternative for pain management, potentially alleviating concerns related to the opioid epidemic.
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Background: Evidence-based international expert consensus regarding the impact of peripheral nerve block (PNB) use in total hip/knee arthroplasty surgery.

Methods: A systematic review and meta-analysis: randomized controlled and observational studies investigating the impact of PNB utilization on major complications, including mortality, cardiac, pulmonary, gastrointestinal, renal, thromboembolic, neurologic, infectious, and bleeding complications.Medline, PubMed, Embase, and Cochrane Library including Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, NHS Economic Evaluation Database, were queried from 1946 to August 4, 2020.

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