The effect of TLR3 priming conditions on MSC immunosuppressive properties.

Background: Mesenchymal stromal cells (MSCs) have regenerative and immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors (TLRs) in MSCs respond to viral load by secreting immunosuppressive or proinflammatory molecules. The expression of anti-inflammatory molecules in MSCs can be altered by the concentration and duration of exposure to the TLR3 ligand polyinosinic-polycytidylic acid (poly(I:C)).

Free Will as a Paradox: Empirical Evaluation of the Construct of Everyday Consciousness.

Background: Free will belongs to the category of phenomena that are actively discussed in scientific discourse but are neither verified nor proven false. Free will is studied in philosophy, neuroscience, and psychology. We discuss this pluralism, multiplicity of perceptions, and the parties' arguments in the theoretical part of this article.

[Dynamics of the emotional state and physiological parameters of the organism during long-term aqua-thermal impact].

Unlabelled: The data presented in this article illustrate the dynamics of the affective sphere of the mental processes associated with the higher nervous activity and the characteristics of the neuroendocrine system (including the vegetative index of Kerdo, cortisol and serotonin levels) in the participants of the marathon swimming competition covering the distance of 101.4 km. We investigated the relationship between the levels of the above hormones and the functional activity of the vegetative nervous system.