The correlation between differentiation of tumor cells in different directions (toward the foveolate epithelium or glandular epithelium in stomach, or small and large intestine epithelium, or endocrine cells) and the state of gastric mucosa (differentiation of its cells in direction of foveolate epithelium or glandular epithelium (hypoplasia of corresponding epithelium), or appearance of focals of metaplasia in small or large intestines, or pronounced hyperplasia of endocrine cells) was revealed in most cases of gastric cancer. The other of the disease did not reveal such correlation.
View Article and Find Full Text PDFProspects of using the nucleolar organizer region (NOR) identification by silver nitrate for the diagnosis of dysplasias and cervical cancer were studied. Four groups of patients (22 cases) have been examined: group 1 (7 cases)--unchanged endocervical epithelium, group 2 (6 cases)--dysplasia of cervical epithelium of degree II-III, group 3 (3 cases)--carcinoma in situ, group 4 (6 cases)--invasive squamous cell nonkeratinizing carcinoma. The investigation showed that there are reliable differences in the quantity of silver granules per nucleus and also of NOR index between normal ectocervical epithelium and dysplasia, normal ectocervical epithelium and cancer, dysplasia and cervical cancer.
View Article and Find Full Text PDF21 surgically removed gastric carcinomas of different histologic structure and stage of development were studied ultrastructurally. A variety of morphological manifestations of local immune reactions and nonspecific antitumour resistance were observed. These manifestations were characterized by the contacts of lymphocytes, macrophages, polymorphonuclear leukocytes, plasma cells with each other and with tumour cells and by the presence of variable changes in tumour cells.
View Article and Find Full Text PDFArkh Patol
September 1989
A case of stomach carcinoma was examined in a 45-year-old male by using histochemical and electron microscopic techniques. The carcinoma had arisen from chronic gastric ulcer accompanied with fundic gland hyperplasia and located in the body of the stomach. Histologically, it was a nondifferentiated scirrhous carcinoma involving signet ring and minor polymorphic cells with eosinophilic cytoplasm.
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