Publications by authors named "E A Demchuk"
Article Synopsis
- Environmental exposures are common and significantly affect public health, leading to chronic and infectious diseases, but there's a lack of comprehensive data on the health impacts of these contaminants.
- Simulation science has emerged as a solution to address data gaps by using computational methods like PBPK modeling and QSAR modeling to assess environmental health risks more efficiently.
- The ATSDR (Agency for Toxic Substances and Disease Registry) effectively utilizes these simulation tools, gaining recognition from external researchers and collaborating across various sectors to enhance public health protection.
Article Synopsis
- Asthma and COPD diagnosis in Russia is problematic, leading to public health issues and economic costs due to inadequate control and diagnostics.
- Effective strategies for improvement include educational initiatives, advanced examination methods, mobile health outreach, and digital medical information systems.
- Utilizing modern approaches in diagnosis and management can enhance patient quality of life and minimize risks of complications and exacerbations.
For short-term chemical inhalation exposures to hazardous chemicals, the incidence of a health effect in biological testing usually conforms to a general linear model with a probit link function dependent on inhalant concentration C and the duration of exposure t. The National Academy's Acute Exposure Guideline Levels (AEGLs) Committee relies on these models when establishing AEGLs. Threshold concentrations at AEGL durations are established by the toxic load equation C x t = constant, which toxic load exponent n (TLE or n-value) directly follows from the bivariate probit model.
View Article and Find Full Text PDFObjective: Dimethyl sulfide (DMS, CAS 75-18-3) is an industrial chemical. It is both an irritant and neurotoxicant that may be life-threatening because of accidental release. The effects of DMS on public health and associated public health response depend on the exposure concentration and duration.
View Article and Find Full Text PDFPolypharmacy increasingly has become a topic of public health concern, particularly as the U.S. population ages.
View Article and Find Full Text PDF