Publications by authors named "E A Defranco"

Background: Chronic kidney disease is a significant cause of adverse obstetric outcomes. However, there are few studies assessing the risk of severe maternal morbidity and mortality among patients with chronic kidney disease and no studies assessing the association between individual indicators of severe maternal morbidity and chronic kidney disease.

Objective: To evaluate the risk of severe maternal morbidity and mortality among pregnant patients with chronic kidney disease.

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  • - Intimate partner violence (IPV) is a significant issue, with about 25% of women in the U.S. experiencing related trauma, but its prevalence among pregnant women is less understood.
  • - A study involving 606 women at an academic hospital from 2011 to 2022 found that 20.4% of participants reported experiencing IPV, with factors like unmarried status, low income, and substance use during pregnancy linked to higher IPV risk.
  • - The research highlights that while maternal race was not directly associated with IPV, experiences of racial and gender discrimination were significant, suggesting that addressing social determinants of health could better support pregnant individuals facing IPV.
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  • * Results showed that pregnant patients with CVD faced significantly higher risks: 11.6% experienced SMM and the maternal death rate was 538 per 100,000, compared to 0.7% and 5 per 100,000 in those without CVD.
  • * Notably, chronic heart failure patients had the highest SMM risk, and Black patients with CVD had a disproportionately higher SMM risk, highlighting existing racial disparities in maternal health outcomes.
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Objective:  Non-Hispanic Black individuals are disproportionately affected by preterm birth (PTB), a major driver of the racial disparity in infant mortality in the United States. The objective of this study is to identify indicators of social determinants of health (SDoH) that contribute to preterm birth amongst non-Hispanic Black individuals.

Study Design:  Population-based retrospective case-control study of U.

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Objective: Infant sleep problems are common in early infancy and can negatively influence maternal-infant bonding. As opioid-exposed neonates are at increased risk of sleep difficulties, we examined the association between maternal perception of infant sleep difficulties and maternal-infant bonding among dyads affected by maternal opioid use disorder (OUD), from birth through 6 months.

Methods: We enrolled 100 birthing people (participants) between 6 months and 2 years postpartum who had received medications for OUD during their pregnancy.

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