Publications by authors named "E A DeFranco"

Background: Following maternal COVID-19 vaccination, the persistence of antibodies in sera and breast milk for mothers and infants is not well characterized. We sought to describe the persistence of antibodies through 2 months after delivery in maternal and infant serum and breast milk following maternal COVID-19 mRNA vaccination and to examine differences by receipt of booster dose during pregnancy or postpartum.

Methods: This is a prospective cohort study with enrollment from July 2021 to January 2022 at 9 US academic sites.

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Background: Chronic kidney disease is a significant cause of adverse obstetric outcomes. However, there are few studies assessing the risk of severe maternal morbidity and mortality among patients with chronic kidney disease and no studies assessing the association between individual indicators of severe maternal morbidity and chronic kidney disease.

Objective: To evaluate the risk of severe maternal morbidity and mortality among pregnant patients with chronic kidney disease.

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Article Synopsis
  • - Intimate partner violence (IPV) is a significant issue, with about 25% of women in the U.S. experiencing related trauma, but its prevalence among pregnant women is less understood.
  • - A study involving 606 women at an academic hospital from 2011 to 2022 found that 20.4% of participants reported experiencing IPV, with factors like unmarried status, low income, and substance use during pregnancy linked to higher IPV risk.
  • - The research highlights that while maternal race was not directly associated with IPV, experiences of racial and gender discrimination were significant, suggesting that addressing social determinants of health could better support pregnant individuals facing IPV.
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  • * Results showed that pregnant patients with CVD faced significantly higher risks: 11.6% experienced SMM and the maternal death rate was 538 per 100,000, compared to 0.7% and 5 per 100,000 in those without CVD.
  • * Notably, chronic heart failure patients had the highest SMM risk, and Black patients with CVD had a disproportionately higher SMM risk, highlighting existing racial disparities in maternal health outcomes.
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Objective:  Non-Hispanic Black individuals are disproportionately affected by preterm birth (PTB), a major driver of the racial disparity in infant mortality in the United States. The objective of this study is to identify indicators of social determinants of health (SDoH) that contribute to preterm birth amongst non-Hispanic Black individuals.

Study Design:  Population-based retrospective case-control study of U.

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