[Evolutional model of sensopathic disorders].

The purpose of this study was to analyze the subjective mechanisms of symptomogenesis (semantogenesis) of disturbed body perception in psychosis. Three groups of psychiatric patients (58 with schizophrenic spectrum disorders, 15 with affective disorders and 32 with organic disorders) with pathological body sensations (sensopathies) and 64 controls with somatic disorders accompanied by pain were studied clinically and with the Component Language Analysis. Based on the clinical and linguistic analysis of utterances of patients, we propose an evolutionary model that describes the development of sensopathies as a continuum of frustration arising from a so-called protopathic shift, the further formation and differentiation of which is provided by subjective (linguistic, first of all) factors of symptomogenesis, which we understand as sematogenesis (the sense formation).

[Morphological diagnosis and pathogenesis of non-developing pregnancy in antiphospholipid syndrome].

20 medical abortions and uterine scrapes from 24 females with verified antiphospholipid syndrome (APS) were studied by light and electron microscopy. Principle parts of pathogenesis are distinguished in the mother organism, target-organs, placenta and uterine-placental region. Morphological criteria of APS diagnosis, in part histo-ultrastructural, pathology of microvilli of brush-border, pathology of syncitiotrophoblast and villous cytotrophoblast.