TAK1 inhibition increases proliferation and differentiation of chick retinal cells.

The factors necessary for the differentiation of cell types within the retina are incompletely understood. The transforming growth factor beta (TGF-β) superfamily, including TGF-β1 and 2, the bone morphogenetic proteins, and the activins have all been implicated in differentiation; however, the mechanisms by which these factors affect differentiation are only partially understood. The studies herein focus on a potential role for transforming growth factor β-activated kinase 1 (TAK1), a hub kinase that lies at the intersection of multiple signaling pathways, in the differentiation of cell types within the chick retina.

Do You Need the Machine? Tipping in Canada Is Unconscious (Part II).

While recovering from a major personal tipping point (see Part I), I was still able to keep on the lookout for Canadian mathematics education matters. After all, if Canadian mathematics education matters, Canadian mathematics education matters. In doing so, I ran into a number of other financial problems.

Do You Need 'The Machine'? Tipping in Canada Is Unconscious (Part I).

Constantly on the lookout for Canadian mathematics education matters, I recently experienced a major personal tipping point. The juxtaposition of two different customer service situations was simply too much for me to handle. Now through the looking glass, it was abundantly clear that tipping in Canada is unconscious, and the evidence was everywhere.

The Metre as a Metric: Canada's COVID-19 Conversion Kerfuffle.

As a Canadian mathematics educator, I have a vested interest in Canadian mathematics education matters. After all, to me, Canadian mathematics education matters. Knowing this little factoid, imagine my horror when it recently dawned on me that, no matter where I looked during this COVID-19 pandemic, all I saw was flippant treatment towards the metric system.