Publications by authors named "E A Biryukova"
Article Synopsis
- The study investigated the presence of anti-podocyte antibodies, specifically targeting synaptopodin and annexin 1, in patients with nephrotic syndrome to evaluate their role in diagnosing primary podocytopathies like Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS).
- A total of 72 nephrotic syndrome patients were analyzed, alongside 21 healthy individuals, finding higher antibody levels in MCD and FSGS patients compared to the others, indicating their potential use in diagnosis.
- The combined analysis of both antibody types showed significant diagnostic accuracy (sensitivity of 80.9% and specificity of 81.3%), although these antibody levels did not predict how well patients
We present the findings of assessing the expression levels of extracellular TLR2 and TLR4 and intracellular TLR3 and TLR8 correlating with the severity of clinical manifestations of HPV infection. A total of 199 women took part in a single-center prospective comparative research study on TLR2, TLR3, TLR4 and TLR8 expression in HPV-related cervical lesions. TLRs' mRNA expression was analyzed using real-time reverse transcription polymerase chain reaction (RT-PCR).
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- Nephrotic syndrome (NS) is linked with a higher risk of thrombosis, but standard tests fail to reveal the actual coagulation issues, while global tests like thrombodynamics (TD) show promise for assessment.
- The study analyzed 94 patients with chronic glomerulonephritis (CGN), finding that TD identified hypercoagulability in a significantly higher percentage of NS patients compared to routine tests, with spontaneous clot formation noted in many.
- Key risk factors for thromboembolic events included older age, elevated lipid levels, glucocorticosteroid use, and TD-detected clots, with no correlation found between these events and routine hemostasis issues.
Disorders of the mineral balance often determine the symptoms, the severity of the course and the prognosis of many diseases. Primary hyperparathyroidism (PHPT) is a common endocrine disease caused by increased secretion of parathyroid hormone as a result of primary damage to the parathyroid glands. Diagnosis of PHPT is often difficult.
View Article and Find Full Text PDFWe studied the effect of biogenic ferrihydrite nanoparticles synthesized as a result of the culturing of Klebsiella oxytoca on Wistar rats with experimental toxic hemolytic anemia. The pathology was simulated by single intraperitoneal injection of phenylhydrazine hydrochloride. On day 4, the functional parameters of erythrocytes in rats corresponded to the state of toxic hemolytic anemia.
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