Publications by authors named "E A Berkowitz"

Introduction: Herein, we report on the option and clinical advantage of the Preserflo MicroShunt insertion into the posterior chamber ciliary sulcus in a patient with advanced pseudoexfoliation glaucoma at a high risk of corneal decompensation.

Case Presentation: We describe a 64-year-old advanced pseudoexfoliation glaucoma patient who despite maximal tolerated medical therapy and two failed glaucoma surgeries, still suffered from uncontrolled intraocular pressure (IOP) of 36 mm Hg in his left eye. The patient underwent the implantation of the Preserflo MicroShunt.

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Background: This retrospective study aims to evaluate the impact of a content-based image retrieval (CBIR) application on diagnostic accuracy and confidence in interstitial lung disease (ILD) assessment using high-resolution computed tomography CT (HRCT).

Methods: Twenty-eight patients with verified pattern-based ILD diagnoses were split into two equal datasets (1 and 2). The images were assessed by two radiology residents (3rd and 5th year) and one expert radiologist in four sessions.

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Systemic lupus erythematosus (SLE), commonly referred to as lupus, is a widely prevalent chronic autoimmune disease that can affect any organ system in the body. Although the pathogenesis of this disease is rather complex and poorly understood, ultimately there is an overproduction of multiple self-reactive antinuclear antibodies. These autoantibodies are one of the laboratory hallmarks of the diagnosis and disease activity of SLE.

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  • The study investigates how the war in Israel has affected physical and mental health among 50 endometriosis patients at Sheba Medical Center through a questionnaire-based approach.
  • Results showed a significant decline in both physical (pain scores increased) and mental health after the war began, with more severe effects observed in those with family involvement in the conflict.
  • Starting new anti-anxiety or antidepressant medications and engaging in psychological therapy helped protect against the negative health impacts, emphasizing the need for early mental health interventions during crises.
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  • Idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) are severe lung diseases that require new treatments, prompting a study on the oral drug admilparant (BMS-986278).
  • A phase 2, randomized, double-blind trial was conducted with 278 IPF patients and 125 PPF patients, who received either 30mg or 60mg of admilparant or a placebo twice daily for 26 weeks, all while allowing background treatments.
  • Results showed that the 60mg dose of admilparant significantly slowed the decline in lung function compared to placebo for both IPF and PPF, with a favorable safety profile, supporting further research in phase 3
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