[Effects of epidural anesthesia on stress-induced immune supression during major corrective spine surgery].

Study Design: A prospective, randomized study wias performed to compare two anesthetic methods.

Objective: To evaluate the effect of epidural analgesia on postoperative pain, endocrine- metabolic and inflammatory stress response and cellular inmmune responses during major corrective spine surgetry.

Methods: The study included 350 patients aged 15 to 65 who were randomly allocated to two equal groups.