Publications by authors named "E A Balas"

Article Synopsis
  • Social determinants of health (SDOH), including factors such as income, insurance status, and marital status, greatly influence the survival rates of patients with gastrointestinal (GI) cancers in the U.S. from 2001 to 2022.
  • A systematic review of 38,654 studies identified 14 relevant studies, revealing that uninsured patients and those with lower incomes had worse survival outcomes, while higher income and being married were linked to better survival rates.
  • The variability in how SDOH factors are studied highlights the need for a more consistent understanding and measurement of these factors to improve strategies aimed at enhancing patient outcomes in GI cancer care.
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Emerging societal expectations from biomedical research and intensifying international scientific competition are becoming existential matters. Based on a review of pertinent evidence, this article analyzes challenges and formulates public policy recommendations for improving productivity and impact of life sciences. Critical risks include widespread quality defects of research, particularly non-reproducible results, and narrow access to scientifically sound information giving advantage to health misinformation.

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Background: Despite recent improvements in melanoma survival rates, persistent inequalities pose barriers to care for some patients.

Objective: To assess the influence of social determinants of health (SDoH) on melanoma treatment outcomes.

Methods: A systematic review (Prospective Register of Systematic Reviews CRD42022346854) of manuscripts that examined the association between SDoH and melanoma treatment-related outcomes in the United States was conducted using 5 databases.

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The number of clinical trials is rapidly growing, and automation of literature processing is becoming desirable but unresolved. Our purpose was to assess and increase the readiness of clinical trial reports for supporting automated retrieval and implementation in public health practice. We searched the Medline database for a random sample of clinical trials of HIV/AIDS management with likely relevance to public health in Africa.

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Significant advancements in public health come from scientific discoveries, but more are needed to meet the ever-growing societal needs. Examining the best practices of outstanding scientists may help develop future researchers and lead to more discoveries. This study compared the comprehensive work of 49 Nobel laureates in Physiology or Medicine from 2000 to 2019 to a matched control of National Institutes of Health (NIH)-funded biomedical investigators.

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