[Identification of haptoglobin as an endogenous inhibitor of prostaglandin H synthetase in the cytosol of sheep vesicular gland cells].

It was shown that sheep vesicular gland cytosol inhibits the peroxidase activity of prostaglandin H synthetase (PGHS). The degree of enzyme inactivation depends on cytosol concentration and incubation time. It was found that cytosol contains a glycoprotein, haptoglobin, which is one of the cytosolic basic components responsible for its ability to inhibit PGHS.

Identification of haptoglobin as an endogenous inhibitor of prostaglandin H synthase in the cytosol fraction of primary cells from sheep vesicular glands.

It was shown that cytosol of primary sheep vesicular gland cells inhibits peroxidase activity of prostaglandin H synthase (PGHS). The degree of the enzyme inactivation depends on cytosol concentration. It was established that cytosol contains glycoprotein haptoglobin that is one of the cytosol basic components responsible for its property to inhibit PGHS.