A Novel Technique of Robotic-Assisted Simple Cystectomy During Urinary Diversion for Benign Indications.

Background: When urinary diversion is necessary for benign indications, the defunctionalized bladder is at risk of a number of severe complications such as bleeding, pain, pyocystis and secondary urothelial carcinoma. These complications occur in 54%-80% of patients left with native bladder after diversion, and these patients go on to require completion cystectomy 20%-25% of the time. Rowley et al.

Intralesional collagenase for acute phase Peyronie's disease: a single-center, retrospective cohort study.

Background: Peyronie's disease (PD) can be subdivided into acute and chronic phases. Intralesional collagenase has been shown to improve curvature in the chronic phase. Initial clinical trials excluded patients in the acute phase from treatment.

Acute Lower Back Pain after Intralesional Injection of Collagenase for Peyronie's Disease.

Purpose: The safety label for collagenase was updated to include postinjection acute lower back pain as an adverse event observed with intralesional therapy for Peyronie's disease. Incidence and causality are unknown. We assessed frequencies and temporal associations for this adverse event in a large cohort.

3D-printed phantoms to quantify accuracy and variability of goniometric and volumetric assessment of Peyronie's disease deformities.

Characterization of Peyronie's disease (PD) involves manual goniometry and penile length measurement. These techniques neglect volume loss or hourglass deformities. Inter-provider variability complicates accuracy.

Rising Black voices in urology - the next generation.

In 2020, made a pledge to actively work towards improving diversity in our field. As we head into 2021, Black urologists make up only 2% of the US workforce in urology; this lack of representation is detrimental to the field as a whole and to the patients it serves. In this Viewpoint, which follows on from our previous article ‘Supporting Black voices in urology’, 12 medical students who have chosen to enter the field recount their experiences, describing their reasons for entering urology and why they chose particular programmes.

Measurement accuracy of 3-Dimensional mapping technologies versus standard goniometry for angle assessment.

Background: A specific aspect of the hypospadias phenotype that may contribute to long-term outcomes is the presence of ventral penile curvature and the adequacy of its surgical correction. The current gold standard to assess this angle is intraoperative goniometry of an erect penis. 3-dimensional (3D) mapping technologies may overcome the limitations of these traditional methods through their combination of digital image and geometric replication to produce consistent 3D digital forms of a physical structure.

Deletion of the von Hippel-Lindau Gene in Hemangioblasts Causes Hemangioblastoma-like Lesions in Murine Retina.

von Hippel-Lindau (VHL) disease is an autosomal-dominant tumor predisposition syndrome characterized by the development of highly vascularized tumors and cysts. LOH of the gene results in aberrant upregulation of hypoxia-inducible factors (HIF) and has been associated with tumor formation. Hemangioblastomas of the central nervous system and retina represent the most prevalent VHL-associated tumors, but no VHL animal model has reproduced retinal capillary hemangioblastomas (RCH), the hallmark lesion of ocular VHL.