Diltiazem is ubiquitously prescribed and has been reported in many effluents and freshwater bodies. Being a calcium channel blocker, diltiazem could disrupt the function of the sensory and central nervous systems. In the present study, using electro-olfactography (EOG), we investigated the interaction of diltiazem with the olfactory sensory neurons (OSNs) of rainbow trout by looking into the detection threshold and effects of immediate (~5 min) and acute (24 h) exposure to diltiazem at 6.
View Article and Find Full Text PDFWith the growth of both the pharmaceutical industry and the human population and longevity, more drugs are used and processed each day. Inevitably, these pharmaceuticals enter wastewater through human excretion and improper disposal of leftovers. One such medication, diltiazem, a calcium channel blocker, is of importance due to its widespread consumption, and prevalence in aquatic environments.
View Article and Find Full Text PDFOil sands process-affected water (OSPW), a byproduct of the extraction of bitumen in the surface mining of oil sands, is currently stored in massive on-site tailings ponds. Determining the potential effects of OSPW on aquatic ecosystems is of main concern to oil sands companies and legislators concerned about the reclamation of mining sites. In the present study, the interaction of OSPW with the chemosensory system of rainbow trout was studied.
View Article and Find Full Text PDFGemfibrozil, a common lipid regulator, enters aquatic environments through treated municipal wastewater effluent that fails to remove it completely from effluent streams. When exposed to gemfibrozil concentrations of 50, 500, 5,000, and 50,000 ng L, Daphnia magna showed increased lipid reserves by 14-21% (significant at 500 ng L), increased length by 9-13% (significant at 50 ng L), increased mass by 6-13% (significant at 50 ng L) and increased neonate production by 57-74% (significant at 50 ng L). Gemfibrozil-exposed Daphnia held under conditions where food availability was low, grew and reproduced as well as those in the control.
View Article and Find Full Text PDFArch Environ Contam Toxicol
April 2018
Oil sands process-affected water (OSPW), which can be potentially toxic to aquatic biota, is a major by-product of bitumen mining in northern Alberta. The effects of environmental factors on the toxicity of OSPW are understudied. In the present study, the impacts of seasonal changes in water quality on the toxic effects of OSPW (1 and 10%) on Daphnia magna was examined.
View Article and Find Full Text PDFThe increasing amount of stored oil sands process-affected water (OSPW), a primary by-product of oil sands mining, is an environmental concern. In the present study, we investigated the chronic effects of OSPW on growth, reproduction, and macronutrient content in Daphnia magna. To do so, we exposed D.
View Article and Find Full Text PDFGrowth in extraction of bitumen from oil sands has raised concerns about influences of this industry on surrounding environments. Water clearance rate (a surrogate of feeding rate by Daphnia magna) in water containing D. magna exposed to oil sands process-affected water (OSPW) and its principal components, dissolved component (DC) and suspended particulate matter (SPM), was reduced to 72, 29, and 59% of controls, respectively.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2017
Cladoceran are animals of significant importance to freshwater bodies such that changes in their populations may result in drastic shifts in the food web. Numerous studies have investigated the effects of toxicants, and the effects of chemical and physical habitat changes to these animals. Most of these studies investigated more general endpoints such as mortality, reproduction, growth, and food consumption over time, and less frequently examined molecular endpoints such as enzyme activity or gene expression.
View Article and Find Full Text PDFThere is growing concern that freshwater ecosystems may be negatively affected by ever-increasing anthropogenic inputs of extremely hard, highly alkaline effluent containing large quantities of Ca(2+), Mg(2+), CO3(2-), and HCO3(-) ions. In this study, the toxicity of rapid and extreme shifts in water hardness (38-600mg/L as CaCO3) and alkalinity (30-420mg/L as CaCO3) to Daphnia magna was tested, both independently and in combination. Within these ranges, where no precipitation event occurred, shifts in water hardness and/or alkalinity were not toxic to D.
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