The longevity factor spermidine is part of a highly heritable complex erythrocyte phenotype associated with longevity.

Extreme longevity in humans is known to be a heritable trait. In a well-established twin erythrocyte metabolomics and proteomics database, we identified the longevity factor spermidine and a cluster of correlated molecules with high heritability estimates. Erythrocyte spermidine is 82% heritable and significantly correlated with 59 metabolites and 22 proteins.

Gamma spectrum and coincidence summation simulations with Geant4 in the analysis of radionuclide using BEGe detector.

A Geant4 application has been developed to simulate the gamma spectrum of a BEGe detector. The summation effects were encompassed for both random and true coincidences through a time-based approach. The application well reproduces the typical spectral features such as full energy peaks, escape peaks, summation peaks and Compton/backscatter continuum.