Publications by authors named "Dylan Lukes"

Article Synopsis
  • Vertebrogenic pain, often linked to damage in vertebral endplates, is transmitted through the basivertebral nerve (BVN) and is associated with Modic changes visible on MRI.
  • A five-year follow-up of three clinical trials assessing intraosseous radiofrequency ablation (BVNA) shows significant pain and functional improvement in patients with chronic low back pain.
  • Out of 320 participants, 249 (78%) completed the study, revealing major reductions in pain scores and enhancements in disability index, demonstrating BVNA as an effective treatment option.
View Article and Find Full Text PDF
Article Synopsis
  • Randomized trials show intraosseous basivertebral nerve ablation (BVNA) is more effective than sham and standard care for improving pain and quality of life in chronic low back pain patients.
  • * The study aims to evaluate the cost-effectiveness of BVNA compared to standard treatment for vertebrogenic chronic low back pain.
  • * Results indicate that BVNA is cost-effective, with an incremental cost-effectiveness ratio (ICER) of US$11,376 per quality-adjusted life year (QALY) over five years, suggesting over 99% probability of being cost-effective at a $100,000 willingness-to-pay threshold.
View Article and Find Full Text PDF

Solving the atomic structure of metallic clusters is fundamental to understanding their optical, electronic, and chemical properties. Herein we present the structure of the largest aqueous gold cluster, Au(p-MBA) (p-MBA: para-mercaptobenzoic acid), solved by electron micro-diffraction (MicroED) to subatomic resolution (0.85 Å) and by X-ray diffraction at atomic resolution (1.

View Article and Find Full Text PDF