Publications by authors named "Dylan E Davis"
Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP.
Acta Crystallogr F Struct Biol Commun
January 2025
Helicobacter pylori, a type 1 carcinogen that causes human gastric ulcers and cancer, is a priority target of the Seattle Structural Genomics Center for Infectious Disease (SSGCID). These efforts include determining the structures of potential H. pylori therapeutic targets.
View Article and Find Full Text PDFCrystal structure of glutamyl-tRNA synthetase from Helicobacter pylori.
Acta Crystallogr F Struct Biol Commun
December 2024
Article Synopsis
- * There is a growing need for alternative treatments due to drug resistance in H. pylori, leading to research at the Seattle Structural Genomics Center for Infectious Disease (SSGCID) into potential drug targets, specifically Glutamyl-tRNA synthetase (GluRS).
- * The SSGCID has successfully determined the structure of H. pylori GluRS, which shares significant similarities with other bacterial GluRS, presenting opportunities for drug discovery aimed at developing new antibacterials to combat H. pylori infections.