Substance P and intensity of pruritus in hemodialysis and peritoneal dialysis patients.

Background: Uremic pruritus is a common complication in patients undergoing dialysis. The pathophysiological mechanisms of pruritus in patients with end-stage renal disease remain unknown. Neuropeptides, including substance P, are postulated to play an important role in the pathogenesis of pruritus.

[Influence of salmon calcitonin on changes in thyroid hormone concentration and on TSH secretion. II].

The aim of this investigation was determination of salmon calcitonin (SC) administration influence on hypothalamus-pituitary-thyroid axis. The investigation was carried out on a group of 26 patients. The group was divided in two different ways: into people younger and older than 65 years, and into men and women.

[The influence of salmon calcitonin on changes in thyroid hormone concentration and on TSH secretion. I].

The aim of this investigation was determination of salmon calcitonin (sCT) influence on changes of thyroid hormones levels in serum. The investigation was carried out on a group of 26 patients. The group was divided in two different ways: into people younger and older than 65 years, and into men and women.

[Arrhythmia in elderly patients as a manifestation of disturbed function of the hypophyseal-thyroid axis].

The purpose of the performed studies was finding the answer to the question: what is the function of hypophyseal-thyroid axis in patients admitted to hospital due to atrial fibrillation? Apart from cognitive premises, the work has also a practical aspect.

[Effect of working conditions in the coke-processing department on the secretory function of the adrenal cortex].

In 85 randomly chosen employees of the coal tar distillation department working at least 5 years, exposed to toxic substances not exceeding MAC except tar substances and benzo(a)pyrene, whose concentrations were high, blood level of cortisol and 17 OHCS and 17 KS excretion in urine were examined. In the most exposed group cortisol level decreased and the 17 OHCS excretion augmented.

[Clinical and patho-morphological evaluation of patients dying from bronchial asthma].

Mortality from asthma within 1978-1987 was analysed retrospectively. This analysis included selected factors determining the mortality in this disease. Some conditions being able to decrease death risk in asthmatic patients were defined.

[Effect of work in hot shops at the coke-processing plant on the liver and gastrointestinal tract].

253 cooking plant workers employed for 5 years were examined. 207 of them were exposed to very high concentrations of BaP and tar substances, as well as to benzene, its homologues and CO at concentrations not exceeding MAC values. In 20% of the examined workers of the baking ovens department exposed to very high BaP concentrations an abnormal activity of marker enzymes was demonstrated, while in 63% of workers C-14 aminopyrine test was pathologic.