Publications by authors named "Dwi Wahyu"
Introduction: Extraskeletal Ewing's Sarcoma is a rare entity of sarcoma that develops rapidly within soft tissue in any anatomic region, and the symptoms depend on its location.
Case Presentation: The X-ray examination of a 28-year-old man with shortness of breath, cough, weight loss, and chest pain showed malignant round cell, in which confirmed by immunohistochemical examination. The examination indicated positive Vimentin findings in the cytoplasm and positive FLI-1 in the nuclei of the tumour cells.
Excessive release of interleukin-6 (IL-6) during the progression of coronavirus disease 2019 (COVID-19) induces cytokine storms, resulting in multi-organ damages including liver injury, similar in nature with mechanism of viral hepatitis. Systemic IL-6 has been associated with the incidence of liver injury among COVID-19 patients; however, studies on IL-6 expression in the liver tissue are completely lacking. The aim of this study was to measure the IL-6 expression in the liver tissues and to determine its correlation with the degree of liver injury in fatal COVID-19 patients.
View Article and Find Full Text PDFIntroduction: In COVID-19 patients, Interleukin-6 (IL-6) will increase, and the production of antigens will be excessive, which will cause excessive inflammation of the tissues, especially the respiratory tract, which causes fibrosis in the lungs and can lead to death.
Objective: To analyze IL-6 expression of lung tissue in COVID-19 patient severity.
Methods: The study is an observational analytic design from July to December 2020.
Article Synopsis
- l-DOPA is a main treatment for Parkinson's disease but can lead to a complication known as l-DOPA-induced dyskinesia (LID) over time.
- Researchers created a mouse model to study LID by administering l-DOPA and recording neuron activity in key brain regions while observing different states of dyskinesia.
- Findings revealed altered neuronal firing patterns in the globus pallidus and substantia nigra during dyskinesia states, indicating that certain pathways that promote movement are enhanced while those that inhibit it are suppressed, contributing to the development of LID.