Acanthus ilicifolius Methanolic Extract for Oral Candidiasis Treatment through Tongue Epithelial STAT3 and Cell Death Evaluation.

Objectives:  This study aimed to evaluate the effects of topical application of methanolic extract on signal transducer and activator of transcription 3 (STAT3) expression and tongue epithelial cell death caused by oral candidiasis under immunosuppressive conditions.

Materials And Methods:  To obtain the oral candidiasis model, 20 healthy male (Wistar) rats were administered oral dexamethasone and tetracycline for 14 days and oral candidiasis was induced with (ATCC-10231) 1 McFarland. They were then randomized into four groups-immunosuppression (K-), oral candidiasis (K + ), nystatin treatment (P1), and 20% methanolic extract treatment (P2) and were treated for 14 days.

The Effect of Anadara granosa Shell's-Stichopus hermanni Scaffold on CD44 and IL-10 Expression to Decrease Osteoclasts in Socket Healing.

Objectives:  This article aimed to investigate the effect of (AG) shell's- scaffold on cluster of differentiation (CD)44 and interleukin-10 (IL-10) expression to decrease osteoclasts in socket healing.

Materials And Methods:  Thirty male Wistar rats were divided into five groups. The lower left incisor was extracted, then given a placebo for group control (K), the treatment group was administered with scaffold from AG shells, and a treatment group with scaffold from blood cockle shell- with the concentration of 0.