[Cerebral perfusion in patients with metabolic syndrome].

Cerebral perfusion was studied in patients with arterial hypertension combined with metabolic syndrome and diabetes mellitus type II. The data is compared to the results obtained for patients with a single disorder--metabolic syndrome, diabetes mellitus type II and arterial hypertension without metabolic alterations. It is shown that patients with disregulation of carbohydrate and lipid metabolism are more vulnerable to cerebral blood supply alterations.

[Body mass loss due to orlistat therapy and multiple factors of cardiovascular risk].

Aim: To study effects of body mass loss due to orlistat on carbohydrate and lipid metabolism, insulin resistance, 24-h profile of arterial pressure (AP), left ventricular myocardial hypertrophy, brain perfusion in patients with metabolic syndrome (MS).

Material And Methods: Thirty middle-aged patients with MS entered the trial. They received orlistat in a dose 120 mg twice a day for 24 weeks.

[Cerebrovascular complications in metabolic syndrome: possible approaches to decrease risk].

Aim: To compare brain perfusion in hypertensive patients with diabetes mellitus type 2 (DM2) or metabolic (MS) syndrome and hypertensive patients without clinicobiochemical signs of DM2 or MS; to study enoxaparin effects on brain perfusion in DM2 and arterial hypertension (AH).

Material And Methods: Seventy patients included in the study were divided into three groups: 30 patients with DM2 and AH (group 1), 30 patients with MS and AH (group 2) and 10 AH patients without manifestations of MS or DM2 (group 3). All the patients have undergone single-photon emission computed tomography (SPECT) of the brain, carbohydrate and lipid metabolism were examined.

[Initial experience with using phosphocreatine in patients in the early (up to 6 hours) period of myocardial infarction].

A randomized study of 60 patients with myocardial infarction (MI) admitted to hospital in the first 6 hours of the disease was performed in order to study the effect of phosphocreatine (PC) on the course of MI. 30 patients were treated with PC; control group consisted also of 30 patients. PC infusion in the early period of MI resulted in the decreased frequency of ventricular arrhythmias (including paroxysms of ventricular tachycardia) and lowered likelihood of cardiac failure development.

[Use of myocardial scintigraphy with 201T1 in combination with the dipyridamole test in patients with ischemic heart disease].

Possible diagnostic use of myocardial 201T1-scintigraphy combined with the dipyridamole test in coronary patients is described. Twenty-six patients were investigated. Coronarography showed atherosclerotic lesions of coronary arteries in 12.

[Clinical evaluation of dynamic scintigraphy of the myocardium with Tl-201 in patients with acute myocardial infarction].

Thirty-six patients hospitalized because of suspicion for acute myocardial infarction (AMI) were examined within the first 24 hours after symptoms of the disease manifested themselves and during the follow-up on days 5-6 and 28-30. Myocardial perfusion was examined using the technique of perfusion myocardial scintigraphy with 201Tl. In cases of an uncomplicated course of AMI, the scintigrams showed a reduction in the area of perfusion defects (a positive time-course) whereas when the disease progressed the scintigrams reflected a negative time-course expressed in an expansion of the area of perfusion defects.

[Diagnostic possibilities of myocardial scintigraphy using T1-201 in acute myocardial infarction].

Myocardial scintigraphic investigation using 201T1 was performed in 36 patients with suspected acute myocardial infarction and 11 clinically normal controls. The scintigrams were assessed visually and using a computer program for semiquantitative assessment of 201T1 distribution across the myocardium. The control subjects' scintigrams show a comparatively even myocardial distribution of the label.

[Myocardial scintigraphy in the diagnosis of infarct in patients with disorders of intraventricular conduction].

Myocardial scintigraphy with pyrophosphate-99mTc-Sn was used as a diagnostic test in 23 patients with different disorders of rhythm and intracardia conduction who were admitted to the department of emergency cardiology of the All-Union Cardiological Scientific Center, Academy of Medical Sciences of the USSR with suspected acute myocardial infarction. Scintigrams were positive in 11 of 12 patients with acute myocardial infarction who were examined in periods of 6 hours of 10 days. One patient examined on the 13th day of the disease had negative scintigrams.