Cataract Surgery Destabilises Temporary the Tear Film of the Ocular Surface.

Background: Symptoms due to dry eye in the form of keratoconjunctivitis sicca (KCS) are often seen after cataract surgery. We investigated the influence of cataract surgery on tear film stability on the ocular surface.

Material And Methods: 60 eyes of 60 patients who underwent cataract surgery were included in a prospective study in 2017 at the Eye Hospital in Hanoi (Vietnam National Institute of Ophthalmology).

Serial intraocular lens opacifications of different designs from the same manufacturer: Clinical and light microscopic results of 71 explant cases.

Purpose: To report clinical findings and light microscopic results of 71 opacified hydrophilic acrylic intraocular lenses (IOLs).

Setting: Vivantes Klinikum Neukoelln, Ophthalmology Department, Berlin, Germany.

Design: Retrospective case series.

Trabecular microbypass stents as minimally invasive approach after conventional glaucoma filtration surgery.

Purpose: To evaluate long-term efficacy and safety of 2 trabecular microbypass stents in patients with advanced primary open-angle glaucoma (POAG) and insufficient intraocular pressure (IOP) after previous filtration surgery.

Setting: Vivantes Klinikum Neukölln, Augenklinik, Berlin, Germany.

Design: Retrospective case series.

Diode laser cyclophotocoagulation versus cyclocryotherapy in the treatment of refractory glaucoma.

Purpose: The aim of the present study was to evaluate the efficacy of diode laser cyclophotocoagulation (DCPC) and cyclocryotherapy (CCT) in the treatment of refractory glaucoma and compare the postoperative complications and discomfort rates.

Methods: In a prospective, randomized, controlled clinical study, 40 eyes of 40 patients with refractory glaucoma were randomly assigned in 2 groups of 20 eyes each to receive either DCPC or CCT. Patients underwent follow-up examinations on the first 3 days and then 1 week and 1, 3, 6, and 12 months after initial treatment.

Biometric evaluation of keratoconic eyes with slit lamp-adapted optical coherence tomography.

Purpose: To evaluate slit lamp-adapted optical coherence tomography for morphological imaging and morphometrical measurements in keratoconic eyes.

Methods: Using slit lamp-adapted optical coherence tomography, we examined 32 eyes of 20 consecutive patients with keratoconus and described morphological attributes of the cornea. Furthermore, in a subgroup of 19 eyes, we measured morphometrical values of the cornea and compared these values with those of an age-matched control group of 19 normal eyes.

Potential use of riboflavin/UVA cross-linking in bullous keratopathy.

Background: Collagen cross-linking of the cornea has been shown by us to have an antiedematous effect in the cornea. The aim of the present study was to examine if this effect can be used for the treatment of bullous keratopathy.

Methods: This clinical interventional case series included 3 patients (3 eyes) with bullous keratopathy due to pseudophakia, corneal transplant rejection, and Fuchs' endothelial dystrophy.

Hydration behavior of porcine cornea crosslinked with riboflavin and ultraviolet A.

Purpose: To examine the influence of a new crosslinking treatment on corneal swelling properties that correlate with the degree of crosslinking.

Setting: Department of Ophthalmology, Vivantes-Klinikum Neukölln, Berlin, Germany.

Methods: Twenty freshly enucleated porcine eyes were crosslinked by applying the photosensitizer riboflavin and ultraviolet-A (UVA) light (370 nm, 3 mW/cm2) for 30 minutes.

Online optical coherence pachymetry to evaluate intraoperative ablation parameters in LASIK.

Purpose: The ablation of corneal tissue with the excimer laser can be variable and can lead to miscorrections. The purpose of this study was to evaluate intraoperative ablation parameters during laser-assisted in-situ keratomileusis (LASIK) with online optical coherence pachymetry (OCP).

Methods: In a prospective, nonrandomized, comparative clinical study, the ablation parameters were continuously assessed intraoperatively with online OCP (Heidelberg Engineering, Lübeck, Germany) in 45 myopic and 10 hyperopic LASIK treatments.

Continuous measurement of corneal dehydration with online optical coherence pachymetry.

Purpose: Online optical coherence pachymetry (online OCP) allows continuous central corneal thickness measurements over time. In this study, the effect of dehydration on corneal tissue was investigated with online OCP.

Methods: Twelve eyes of 11 patients were examined with online OCP, and the central corneal thickness was registered over 5 minutes after insertion of an eyelid speculum.

Imaging interface fluid after laser in situ keratomileusis with corneal optical coherence tomography.

A 41-year-old myopic patient who had laser in situ keratomileusis 6 months earlier was treated for a complete retinal detachment (RD) with proliferative vitreoretinopathy. Surgical treatment consisted of an encircling band, pars plana vitrectomy, and silicone oil filling. Postoperatively, the patient developed marked corneal edema with no increase in intraocular pressure (IOP) as measured by applanation tonometry.

Influence of cataract surgery on corneal endothelial cell density estimation.

Purpose: To assess the effect of cataract surgery on semiautomated human corneal endothelial cell density (ECD) estimation using noncontact specular microscopy.

Methods: In this prospective clinical study, 62 consecutive patients undergoing cataract surgery were studied. To evaluate possible variations of accuracy and agreement under clinical circumstances, the corneal ECD was determined before and after cataract surgery.

Noncontact goniometry with optical coherence tomography.

Objective: To assess the value of noncontact goniometry with optical coherence tomography (OCT) compared with current clinical parameters in the evaluation of the anterior chamber angle (ACA).

Design: Prospective observational study of 138 eyes of 109 patients.

Methods: The ACA parameters and angle-opening distance (AOD) were measured with slitlamp-adapted OCT goniometry.

Continuous monitoring of corneal thickness changes during LASIK with online optical coherence pachymetry.

Purpose: To assess the continuous intraoperative monitoring of central corneal thickness (CCT) changes during laser in situ keratomileusis (LASIK) using online optical coherence pachymetry (OCP).

Setting: Department of Ophthalmology, Vivantes Klinikum Neukolln, Berlin, Germany.

Methods: In this prospective nonrandomized comparative clinical case series of consecutive patients, 32 eyes having LASIK for myopia, myopic astigmatism, or hyperopia were continuously monitored intraoperatively in real time with online OCP integrated into a clinical excimer laser.

Lamellar keratotomy to correct astigmatism in cataract surgery.

Background: For the correction of astigmatism in cataract surgery, several incisional procedures have been developed. In this study, a modification of lamellar keratotomy was evaluated to correct astigmatism in cataract surgery.

Methods: Prospectively 32 eyes of 25 patients with a preoperative astigmatism greater than 1.

Monitoring corneal structures with slitlamp-adapted optical coherence tomography in laser in situ keratomileusis.

Purpose: To monitor corneal structures with slitlamp-adapted optical coherence tomography (OCT) in laser in situ keratomileusis (LASIK).

Setting: Department of Ophthalmology, Vivantes Klinikum Neukölln, Berlin, Germany.

Methods: In this prospective, nonrandomized, comparative clinical case series of consecutive patients who had LASIK for myopia and myopic astigmatism, the corneal structures were studied with slitlamp-adapted OCT at a wavelength of 1,310 nm.

Influence of indocyanine green staining on the biomechanical strength of porcine internal limiting membrane.

Purpose: Indocyanine green (ICG) has recently been introduced to stain selectively the internal limiting membrane (ILM) of the retina for ILM peeling. The aim of the present in vitro study was to examine the effect of ICG staining on the biomechanical properties of porcine ILM.

Methods: Two parallel 10 x 7 mm strips of central retina were prepared from each of the 40 porcine eyes.

Imaging and quantification of calcified corneal lesions with optical coherence tomography.

Purpose: The purpose of this study was to image and quantify calcified corneal lesions with optical coherence tomography (OCT) and to evaluate this diagnostic method to assess this corneal disease.

Methods: In a clinical study 15 eyes of 14 patients with calcified corneal lesions in the anterior portions of the cornea were assessed with slit-lamp biomicroscopy and slit-lamp-adapted OCT. The qualitative and quantitative optical changes were compared with the clinical findings.

Biomechanical changes in the anterior lens capsule after trypan blue staining.

Purpose: To examine the effect of trypan blue staining on the biomechanical behavior of the porcine anterior lens capsule.

Setting: Department of Ophthalmology, Technical University of Dresden, Dresden, Germany.

Methods: Fifty-five anterior lens capsules from porcine cadaver eyes were used.

Imaging scleral expansion bands for presbyopia with optical coherence tomography.

A 57-year-old woman was treated for mild presbyopia with implantation of scleral expansion bands (SEB). Although near vision was temporarily restored, the effect dissipated after 1 year. Slitlamp-adapted optical coherence tomography (OCT) at 1310 nm allowed precise cross-sectional visualization of the hyporeflective intrascleral segments.

Experimental evaluation of online optical coherence pachymetry for corneal refractive surgery.

Purpose: Online optical coherence pachymetry (OCP) allows to monitor central changes of the corneal cross section intraoperatively. In this experimental evaluation the validity of the optical measurements for corneal refractive surgery was assessed.

Methods: Online OCP based on low-coherence interferometry with a wavelength of 1310 nm and a measurement frequency of 74 Hz was directly integrated in a clinical excimer laser.

[Evaluation of posterior capsule opacification after implantation of the Akreos Disc and Akreos Fit acrylic intraocular lenses - pilot studies].

In the course of the past few years the incidence of secondary cataract has reduced continually due to advanced surgical technique and better lens material and design. To evaluate the progression of posterior capsule opacification (PCO) and IOL-decentration after implantation of two hydrophilic acrylic intraocular lenses (IOL) we set up two pilot studies at two different ophthalmological surgical centres. After extracapsular cataract extraction 15 patients got the Akreos Disc-IOL (Bausch and Lomb) and 12 patients the Akreos Fit-IOL (Bausch and Lomb) implanted.