The association of magnetic resonance imaging features with five molecular subtypes of breast cancer.

Objective: To identify the association of magnetic resonance imaging (MRI) features with molecular subtypes of breast cancer (BC).

Materials And Methods: A retrospective study was conducted on 112 invasive BC patients with preoperative breast MRI. The confirmed diagnosis and molecular subtypes of BC were based on the postoperative specimens.

Stress and sleep quality in medical students: a cross-sectional study from Vietnam.

Background: The COVID-19 pandemic has resulted in significant global social and economic disruptions, as well as changes in personal attitude and behavior. The purpose of this research is to assess the sleep quality and stress levels of medical students.

Method: Data was collected from medical students over the course of a month in 2021.

Intra-atrial Reentrant Tachycardia in Complete Transposition of the Great Arteries Without Femoral Venous Access.

Catheter ablation for patients with transposition of the great arteries (d-TGA) requires multiple considerations and careful preprocedural planning. Knowledge of the patient's anatomy and surgical correction, in addition to electroanatomic mapping and entrainment maneuvers, are important to identify and successfully treat arrhythmias. This case was unique in that the lack of femoral venous access required transhepatic venous access and bidirectional block was attained with ablation lesions along the cavotricuspid isthmus on both sides of the baffle.

Slow Pathway Modification in a Patient with D-Transposition of the Great Arteries and Atrial Switch Procedure.

Patients with systemic right ventricles are often not able to tolerate frequent, rapid, or incessant atrial arrhythmias without developing significant symptoms and ventricular dysfunction. Atrial arrhythmias are associated with an increased risk of ventricular arrhythmias and sudden cardiac death. Rhythm disturbances must be aggressively addressed in this population with frequent screening, follow-up, and treatment.

A Case of Cough-induced Ventricular Tachycardia in a Patient with a Left Ventricular Assist Device.

In this case, the patient's ventricular tachycardia (VT) was specifically induced by coughing, which has not previously been described. Decreasing the rotational speed of the left ventricular assist device (LVAD) and increasing preload by stopping the patient's nitrates and reducing diuretic dose allowed improved filling of the left ventricle (LV) and increased LV volumes. When coughing recurred, the effects on the LV cavity were less pronounced and thus VT was reduced.

Ablation of Atrial Fibrillation in a Patient with a Mechanical Mitral Valve.

Clinicians must be mindful of the left ventricular lead when cannulating the coronary sinus with a decapolar catheter or an ablation catheter. Left atrial catheter ablation for the treatment of atrial fibrillation in patients with a mechanical mitral valve, when approached carefully, can be performed safely and effectively. Block across linear lines should be confirmed using differential activation and/or differential pacing to decrease risks of proarrhythmias.

Ventricular Tachycardia in a Patient with Biventricular Noncompaction.

Patients with ventricular noncompaction are susceptible to developing ventricular tachycardia. Commonly, the origin of ventricular tachycardia is endocardial; however, epicardial origins and scar cannot be excluded and should be considered when poor endocardial mapping is present. Other cardiomyopathies, such as arrhythmogenic right ventricular cardiomyopathy, can coexist with ventricular noncompaction and should be excluded in these patients.

Inhibition of proto-oncogene c-Src tyrosine kinase: toward a new antiarrhythmic strategy?

Cellular-Src (c-Src) encodes a plasma membrane-associated tyrosine protein kinase, which plays a vital role in signaling pathways related to cellular development and carcinogenesis (1,2). It was the first proto-oncogene to be described and is the cellular homologue in humans of the viral oncogene of Rous sarcoma virus, the chicken tumor virus discovered by Peyton Rous in 1911 (3). More recently, c-Src has been implicated in connexin43 (Cx43) remodeling in epicardial border zone myocytes following myocardial infarction (MI) (4).

Preprocedural imaging in patients with transposition of the great arteries facilitates placement of cardiac resynchronization therapy leads.

Objective: The purpose of this study is to review a series of patients with complex congenital heart disease in whom preprocedural imaging was used to assist placement of cardiac resynchronization therapy (CRT) leads.

Background: CRT may be beneficial in patients with a failing systemic ventricle and transposition of the great arteries (TGA). However, complex coronary venous anatomy can be challenging for placement of CRT leads.

Percutaneous transhepatic access for catheter ablation of cardiac arrhythmias.

Aims: Femoral venous access may be limited in certain patients undergoing electrophysiology (EP) study and ablation. The purpose of this study is to review a series of patients undergoing percutaneous transhepatic access to allow for ablation of cardiac arrhythmias.

Methods And Results: Six patients with a variety of cardiac arrhythmias and venous abnormalities underwent percutaneous transhepatic access.