Iron Deficiency in Heart Failure: Characteristics and Treatment.

Purpose Of The Review: Iron deficiency in heart failure has been associated with impaired functional capacity and quality of life. The purpose of this paper is to review mechanisms of iron homeostasis and current clinical data exploring mechanisms of iron repletion in heart failure.

Recent Finding: Multiple international societies now advise iron repletion for symptomatic heart failure patients with iron deficiency.

The Effect of Ranolazine on Glycemic Control: a Narrative Review to Define the Target Population.

Ranolazine is an anti-anginal medication that reduces the sodium-dependent calcium overload via the inhibition of the late sodium current. After its approval for the treatment of chronic angina in 2006 in the USA, ranolazine has been reported to have several pleiotropic effects on various cardiac conditions, such as atrial fibrillation, ventricular arrhythmias, diastolic and microvascular dysfunction, and pulmonary arterial hypertension. Recently, several studies reported some promising results on the potential benefits of ranolazine on glycemic control.