Publications by authors named "Dustin S Chernick"
ACS Chem Biol
October 2016
Article Synopsis
- Protein prenylation helps proteins attach to cell membranes and interact with other proteins, and it's been a key focus for research, especially related to the oncogenic protein Ras as a potential therapy target.
- Recent studies suggest a link between protein prenylation and neurodegenerative diseases like Alzheimer's and Parkinson's.
- The researchers developed a method to image and quantify prenylated proteins in mammalian cells, revealing significant differences between cell types and suggesting that changes in prenylation may be related to impaired cellular processes like autophagy.
