Process optimization of cypermethrin biodegradation by regression analysis and parametric modeling along with biochemical degradation pathway.

Pyrethroid pesticides are of great environmental and health concern with regard to neurotoxicity and ubiquitous occurrence. Here, we reported a new bacterial strain identified as Bacillus cereus AKAD 3-1 that degraded 88.1% of 50 mg/l of cypermethrin in an aqueous medium.

Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease.

A series of hybrid indolo[3,2-c]isoquinoline (δ-carboline) analogs incorporating two pyrimidine and piperizine ring frameworks were synthesized. Intending biological activities and SAR we propose replacements of fluorine, methyl and methoxy of synthetic compounds for noteworthy antimicrobial, antioxidant, anticancer and anti-tuberculosis activities. Among these compounds and were progressively strong against and .