Publications by authors named "Dushyant Singh Dahiya"
Background: Necrotizing pancreatitis (NP), a severe form of pancreatitis characterized by necrosis of pancreatic tissue, is associated with a significant health care burden worldwide. In this study, we assess early readmissions of NP in the US.
Methods: The National Readmission Database from 2016 to 2020 was utilized to identify all index and 30-day readmissions of NP in the US.
Introduction: Gastrointestinal (GI) bleeding is a common and potentially life-threatening medical emergency. Despite advancements in therapy, mortality rates associated with GI bleeding remain high (2.4% to 11%).
View Article and Find Full Text PDFPercutaneous transhepatic cholangioscopy (PTCS) is essential for managing patients with altered biliary anatomy when endoscopic retrograde cholangiopancreatography fails. This study aimed to compare the safety and efficacy of conventional PTCS (C-PTCS) with the SpyGlass PTCS (S-PTCS) system in cases of challenging biliary access. A systematic review and meta-analysis included 12 studies with 998 patients.
View Article and Find Full Text PDFPurpose Of Review: Subepithelial lesions (SELs) are tumors originating from the gastrointestinal (GI) tract wall (muscularis mucosa, submucosa, or muscularis propria) and are covered by overlying mucosa. They are typically incidental findings during routine endoscopy. This article reviews the latest advancements in endoscopic techniques and devices used to resect subepithelial lesions.
View Article and Find Full Text PDFBackground And Aims: Malignant gastric outlet obstruction (MGOO) is an unfortunate adverse event of advanced upper GI malignancies. Historically, surgical gastrojejunostomy (SGJ) has been the procedure of choice to achieve enteral bypass. Recently, endoscopic techniques have gained popularity in the management of MGOO.
View Article and Find Full Text PDFIntroduction: Thermal ablative methods (such as argon plasma coagulation (APC) and soft tip snare coagulation (STSC) are commonly used to treat polyp margins. We aim to appraise the current literature and compare clinical outcomes between patients with treated (with APC vs. STSC) and non-treated endoscopic mucosal resection (EMR) margins.
View Article and Find Full Text PDFPancreatic cancer is associated with high rates of morbidity and mortality. Endoscopic ultrasound (EUS)-guided biopsy has become the standard diagnostic modality per the guidelines. The use of EUS has been growing for providing various treatments in patients with pancreatic cancers: biliary and gallbladder drainage for those with malignant biliary obstruction, gastroenterostomy for malignant gastric outlet obstruction, celiac plexus/ganglia neurolysis for pain control, radiofrequency ablation, placement of fiducial markers, and injection of local chemotherapeutic agents.
View Article and Find Full Text PDF: Sex-related treatment disparities are well-documented across various medical conditions, yet their impact on the management of inflammatory bowel disease (IBD) remains underexplored. This study aims to investigate sex-based differences in the management of ulcerative colitis (UC), focusing on both medical and surgical approaches and examining whether biological sex correlates with variations in healthcare utilization. : A systematic search was conducted across multiple databases, including MEDLINE (via PubMed), Google Scholar, the Cochrane Library, and ScienceDirect, to identify studies on sex differences in ulcerative colitis (UC) management up to April 2024.
View Article and Find Full Text PDFIntragastric balloon adverse events: a comprehensive MAUDE database review.
Proc (Bayl Univ Med Cent)
October 2024
Background: Endoscopic bariatric interventions are viable alternatives to traditional weight loss surgeries for patients with a body mass index between 30 and 40 kg/m. While studies have explored the impact of intragastric balloons on obesity and weight reduction, comprehensive data on real-world device-related complications and failures are limited. This study aimed to investigate mechanical failures leading to patient adverse events reported to the US Food and Drug Administration.
View Article and Find Full Text PDFArticle Synopsis
- Alcohol-related liver disease (ALD) is a growing public health issue, especially among people under 55, leading to an increase in alcohol-attributable deaths that are projected to rise further by 2030.
- Data from the CDC revealed a significant increase in mortality rates, particularly in the 25-34 age group, with rates climbing from 3.9 per 100,000 in 1999 to an expected 14.4 per 100,000 by 2030.
- This upward trend highlights the urgent need for public health interventions to address and reduce ALD mortality rates in younger populations.
Article Synopsis
- The study examines the effectiveness of a new treatment approach in managing a specific health condition, highlighting its potential benefits compared to traditional methods.
- Results from the clinical trials show significant improvements in patient outcomes, suggesting this treatment could become a standard practice.
- The authors emphasize the need for further research to understand long-term effects and refine treatment protocols for broader patient populations.
Article Synopsis
- Patients with decompensated cirrhosis face higher COVID-19 risks, and the study analyzed outcomes based on demographics using SECURE-Liver and COVID-Hep databases.
- In North America, Black patients showed higher rates of hospitalization, ICU admission, and death compared to White patients, while Hispanic patients fared better. In Europe, White patients had more comorbidities but lower hospitalization rates than non-White patients.
- After adjusting for confounders, many disparities in COVID-19 outcomes became statistically insignificant, indicating that other health conditions might contribute to the increased risks rather than demographics alone.
Article Synopsis
- Primary sclerosing cholangitis (PSC) is a liver disease linked to inflammatory bowel disease and can cause serious liver complications; this study investigates trends in healthcare usage and mortality related to PSC in the U.S. from 2008 to 2017.
- The analysis of the Nationwide Inpatient Sample reveals that while hospital charges for PSC patients rose by 32.2%, the average length of hospital stays decreased during the study period, indicating changes in healthcare practices.
- Additionally, there was a notable increase in the severity of illness and risk of death among PSC patients, with a rise in cases of hepatocellular carcinoma (HCC), while cases of cholangiocarcinoma (CCA) saw a decline.
Article Synopsis
- The study focuses on developing a simple risk score model to predict mortality in ICU patients with acute pancreatitis, aiming to improve treatment planning.
- Researchers analyzed data from 380 patients, identifying key predictive variables through advanced statistical methods, ultimately creating a model with five key indicators.
- The final model demonstrated high accuracy in predicting both 7-day and 30-day mortality, outperforming existing prediction scores like BISAP and APACHE-II, thus providing a practical tool for ICU clinicians.
Article Synopsis
- The study evaluated how frailty affects outcomes after endoscopic retrograde cholangiopancreatography (ERCP) in the U.S., using data from the National Readmission Database between 2016 and 2020.
- Among 885,416 ERCP index admissions, 9.9% experienced readmissions within 30 days, with higher readmission rates and odds for those categorized as intermediate and high frailty compared to low frailty.
- Increased frailty also correlated with longer hospital stays and higher hospitalization costs, as well as a greater risk of inpatient mortality for those in the intermediate and high frailty groups.
Objective: Endoscopic submucosal dissection (ESD) is a superior, minimally invasive technique compared with other snare-based endoscopic resection techniques for rectal neoplasms extending to the dentate line (RNDLs). However, performing a successful ESD in the anal canal can be challenging due to vascularity and limited scope stability. In this meta-analysis, we aim to evaluate the safety and efficacy of ESD for RNDLs.
View Article and Find Full Text PDFBackground And Aims: Effect of underwater endoscopic submucosal dissection (UESD) on clinical outcomes as compared with conventional ESD (CESD) remains unclear. We conducted a meta-analysis of the available data.
Methods: Online databases were searched for studies comparing UESD with CESD for colorectal lesions.
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become one of the most popular medications for patients with diabetes and obesity. Due to their effects on gut motility via central or parasympathetic pathways, there have been concerns about an increased incidence of retained gastric contents and risk of aspiration in the perioperative period. Hence, the American Society of Anesthesiologists (ASA) recommends holding GLP-1 RAs on the procedure day or a week before the elective procedure based on the respective daily or weekly formulations, regardless of the dose, indication (obesity or diabetes), or procedure type.
View Article and Find Full Text PDFObjective: Gastric antral vascular ectasia (GAVE) is characterized by vascular ectasias accounting for 4% of nonvariceal upper gastrointestinal bleeds, which can range from occult bleeds to severe acute upper gastrointestinal bleeding. In turn, GAVE can lead to severe morbidity and recurrent hospitalization. Current endoscopic treatments for GAVE include argon plasma coagulation (APC), endoscopic band ligation (EBL), and radiofrequency ablation.
View Article and Find Full Text PDFArticle Synopsis
- Acute necrotizing pancreatitis is a serious condition that challenges healthcare providers due to potential complications, with various necrosectomy procedures available but no clear consensus on the best timing for the operation.
- A national study analyzed data from 2016-2019 to assess the effects of timely necrosectomy (within 48 hours) vs. delayed necrosectomy on patient outcomes, focusing on readmission rates, healthcare use, and mortality.
- Results showed that early necrosectomy had lower readmission rates, reduced need for mechanical ventilation and septic shock, decreased in-hospital mortality, and resulted in lower healthcare costs and shorter hospital stays compared to delayed interventions.
Article Synopsis
- In 2013, the SPIRIT group introduced guidelines to enhance reporting quality in randomized controlled trials (RCTs), specifically targeting studies on endoscopic colorectal cancer screening.
- A review of five RCTs showed adherence to SPIRIT guidelines between 82.4% to 92.2%, with significant gaps in trial registration and informed consent reporting.
- Overall, 37% of participants invited to screening actually underwent the procedure, highlighting discrepancies in protocol adherence, particularly with one trial showing notably lower rates.