Blood group misinformation impacting the attendant's decision-making for a timely blood transfusion to their patient: An ethical dilemma.

In the third week of November 2024, a critical incident involving the refusal of a blood transfusion was reported at our hospital. The case involved a 65-year-old Indian patient who had been admitted for a proposed stoma closure surgery. Although the healthcare team deemed an urgent blood transfusion necessary as part of the patient's treatment plan, the transfusion was refused due to misinformation from the patient's attendants regarding the patient's original blood type.

Implications of Corona Virus Disease-19 pandemic on cytopathology laboratory-Challenges and solutions in resource-limited settings.

Background: Corona Virus Disease-19 (COVID-19) disease which is still showing peaks and plateau with emerging new mutational viral variants has led to the modification of working of hospitals and medical institutes. Cytopathology laboratories geared up with the changing situation to cope up with not only the COVID-19 patients but also patients of other diseases, particularly oncology patients. It was also important to adopt changes in the cytopathology residency program so as to cope up with the changing scenario.

A rare report of H-partially deficient, non-secretor phenotype from India. An A like the rèunion and unlike a Para Bombay-Clarifying misinterpretations.

Background: H-deficient phenotypes are classified as H-deficient non- secretors (Bombay Oh), H-deficient secretors (Para Bombay), and H-partially deficient non-secretors (O reunion, A and B, AB).

Report: We report the first case of H-partially deficient non-secretor- the A phenotype from India. What makes this report interesting is that they do not fit into the Bombay, or the Para Bombay series of H-deficient phenotypes and these partially deficient non-secretors were exclusively found on Réunion Island, off the East Coast of Africa in 1982.

Analytical and Post Analytical Phase of an ISO 15189:2012 Certified Cytopathology Laboratory-A Five Year Institutional Experience.

Objective: Analytical and post analytical phase are integral part of total quality management system and include steps from submission of slides till reports are dispatched. The present study was conducted to analyze the analytical and post analytical phase of the ISO15189:2012 certified cytopathology laboratory. It was also intended to study the various errors which were encountered and steps taken to reduce these discrepancies.

Cytological diagnosis of primary cutaneous histoplasmosis with hemophagocytosis in immunocompetent patient - A rare case from non endemic region.

Histoplasma capsulatum is an opportunistic dimorphic fungus caused by inhalation of spores present in the soil. It is extremely rare in the northern Himalayan region of India and is usually asymptomatic. It may rarely progress to disseminated histoplasmosis which is usually observed in immunocompromised patients associated with malignancy, acquired immunodeficiency syndrome or diabetes.

Effect of autologous PRP on wound healing in dental regenerative surgeries and its correlation with PDGF levels.

Introduction: Autologous platelet-rich plasma (PRP) is the fraction of blood plasma, with increased concentration of platelets, from baseline serum level. Growth factors (GFs) in PRP expedite the soft tissue and bony healing. However, estimation of their levels and role in healing had not been studied extensively.

Blood transfusion safety: A study of adverse reactions at the blood bank of a tertiary care center.

Background: An adverse transfusion reaction (ATR) is an unfavorable reaction to the transfused unit, the severity of which may be different among individuals depending upon the type of reaction and the patient's susceptibility. Transfusion reactions may be immediate or delayed type depending on the onset and immune or nonimmune type depending on the pathogenesis. A study was conducted to study the frequency of various transfusion reactions and the associated morbidity.

Trends of transfusion transmissible diseases among blood donors at uttarakhand, India.

Context: Blood can save lives; however, it can be a source of transfusion transmitted diseases if proper screening of donated blood is not done. It is now mandatory to screen all donated blood units, whether replacement or voluntary for five transfusion transmitted diseases-namely human immunodeficiency virus (HIV), hepatitis B and C, syphilis, and malaria.

Aims: The present study was done to study the prevalence of infectious disease markers among donors at the blood bank of a tertiary care center.

Malaria positivity among blood donors: an important index to assess blood safety.

Blood transfusions carry the potential for causing increased morbidity & mortality both in terms of transfusion reactions as well as transfusion transmitted infections. It is therefore mandatory to test for transfusion transmitted diseases before any unit is transfused to a patient. In India it is mandatory to screen all units for HIV, HBsAg, HCV, Syphilis and Malaria.

Hematological parameters in patients of cleft lip and cleft palate with special reference to eosinophil counts.

Introduction: Birth abnormalities like cleft lip and cleft palate account for about 1.4 per 1000 live births in India. These are seen to be associated with a high incidence of eosinophilia which delays the surgical management of these patients.

Round Cell Vaginal Malignant Melanoma: A rare entity.

Malignant melanoma is predominantly a skin disease but in rare instances it may occur at other sites. A vaginal melanoma is a rare clinical entity and the round cell type is an uncommon variant. Although the present case was clinically diagnosed as a urethral caruncle, on histopathological examination and immunostaining it was diagnosed as a round cell pigmented malignant melanoma.

Male genitourinary tuberculosis--13 years experience at a tertiary care center in India.

We conducted a retrospective study of genitourinary tuberculosis (TB) among males attending a hospital in the northern Himalayan region of India. Records from 1 January 1997 to 31 December 2009 were reviewed for clinical history, relevant radiological findings laboratory data, histopathology and treatment. Of the 1,113 male urogenital non-neoplastic specimens received at the histopathology laboratory of the hospital, tuberculosis was diagnosed in 25 cases (2.

Alcohol intake and cigarette smoking: impact of two major lifestyle factors on male fertility.

Context: Lifestyle factors, like alcohol intake and cigarette smoking, have been reported to affect male fertility.

Aims: To find out the specific impact of alcohol and smoking on semen quality of male partners of couples seeking treatment for primary infertility.

Materials And Methods: From the semen samples analyzed in our andrology laboratory, results of 100 alcoholics and 100 cigarette smoker males were studied following WHO guidelines and compared with 100 strict nonalcoholic and nonsmoker males for presence of asthenozoospermia, oligozoospermia and teratozoospermia.

Utilization of blood and components in a tertiary care hospital.

Purpose: Blood transfusion is an important part of patient management. Indications for blood use must be clear in the mind of ordering clinicians, to avoid its misuse and also to avoid unnecessary exposure of the patient to donor blood antigens, adverse reactions and transfusion transmissible diseases.

Methods: In a retrospective pilot study, details of whole blood and components transfused were noted and correlated with the patient's diagnosis and indications for transfusion, during 1 month.

Hematological malignancies diagnosed by bone marrow examination in a tertiary hospital at Uttarakhand, India.

Introduction: Hematological malignancies are quite common and affect all ages and genders. The diagnosis involves a multiparameter approach. The geographical distribution of various types of hematological malignancies has been provided by various authors but no such data have been published regarding the State of Uttarakhand in India.

Pattern of cancers amongst patients attending Himalayan Institute of Medical Sciences, Dehradun.

This hospital-based study seeks to find out the most common cancers amongst the patients attending Himalayan Institute of Medical Sciences (HIMS), Dehradun, situated in Uttaranchal, which has inadequate health care facilities and low socio-economical status. In our study, of the 20,247 cases reported in the pathology department from July 1996 to Dec. 2003, 18.