[Difficulties in surgical treatment of fixed cardiofundal axial esophageal hiatal hernia].

One of the most common gastrointestinal diseases is esophageal hiatal hernia. It is the third most common disease after peptic ulcer and cholecystitis. We present surgical treatment of a patient with fixed axial cardiofundal hiatal hernia and previous laparoscopic repair of large hiatal hernia.

The Role of Inflammatory and Hemostatic Markers in the Prediction of Severe Acute Pancreatitis: An Observational Cohort Study.

Introduction: Acute pancreatitis (AP) is a serious inflammatory disease of the pancreas that can lead to significant morbidity and increased mortality. The special role of inflammation and disruption of the hemostatic system in the development of severe forms of the disease is known, however, the relationship between inflammatory and anti-inflammatory cytokines and thromboelastogram parameters has not been sufficiently studied.

Aim: The aim of this study is to assess the prognostic significance of thromboelastogram parameters, interleukin-6, and interleukin-22 levels in assessing the risk for developing severe forms of acute pancreatitis.

[Modern endoscopic technologies for chronic calcifying pancreatitis].

Objective: To evaluate the effectiveness and safety of electrohydraulic lithotripsy of calculi of the main pancreatic duct using ultrathin SpyGlass DS endoscope.

Material And Methods: The study included 29 patients with chronic calcifying pancreatitis and obstructive calculi of the main pancreatic duct. All surgeries were carried out between 2018 and 2023.

[Direct transfistulous ultrasound in minimally invasive surgical treatment of infected pancreatic necrosis].

Objective: To develop a method for direct transfistulous ultrasound in minimally invasive treatment of infected pancreatic necrosis.

Material And Methods: There were 148 patients with infected pancreatic necrosis between 2015 and 2019 at the Krasnodar City Clinical Hospital No. 2.

[A modified method for percutaneous drainage of acute necrotic collections in patients with infected pancreatic necrosis].

Objective: To develop a modified method for percutaneous drainage of acute necrotic collections in patients with infected pancreatic necrosis.

Materials And Methods: Minimally invasive surgical technologies were used in 74 patients with infected acute necrotic collections at the Krasnodar Regional Clinical Hospital No. 2 between 2017 and 2019.

[Technological features of open and minimally invasive surgical treatment of local complications of purulent-necrotic pancreatitis].

There are various options for surgical treatment of purulent-necrotic pancreatitis with significant technological differences. Combining surgical methods other than traditional ones into a group of minimally invasive ones based on the principle of the absence of standard laparotomy is not entirely correct. The review presents modern methods of surgical treatment of acute pancreatitis, comparison of their technology regarding classical stages of surgical intervention and their classification.

Transfistulous endoscopic sequestrectomy in the treatment of infected pancreatic necrosis.

Objective: To develop an effective minimally invasive method for the treatment of infected pancreatic necrosis.

Material And Methods: There were 168 patients with infected pancreatic necrosis who were treated at the Regional Clinical Hospital No. 2 between 2011 and 2018.

[Risk factors of surgical treatment in patients with liver cirrhosis].

Objective: To optimize selection of patient for surgical treatment of comorbidities and complications of liver cirrhosis (LC) via analysis of perioperative risk factors.

Material And Methods: There were 610 patients with LC and comorbidities who underwent surgical treatment between 2015 and 2021 at the Regional Clinical Hospital No. 2.

[Minimally invasive treatment of post-burn esophageal perforation].

Perforation of the esophagus is a serious and dangerous condition due to progressive development of mediastinitis and sepsis. This disease is often fatal. In the last decade, endoscopic stenting of the esophagus became more common in these patients as an alternative to traditional surgery.

[Minimally invasive surgical interventions in the treatment of severe acute pancreatitis].

Objective: To improve the outcomes in patients with severe destructive pancreatitis undergoing minimally invasive surgery.

Material And Methods: There were 482 patients with acute destructive pancreatitis for the period from 2007 to 2016. Non-infected acute destructive pancreatitis was diagnosed in 58% (=280) of patients, infected pancreatic necrosis - in 42% (=202) of patients.

[Endoscopic ligation in treatment and prevention of bleeding from esophageal varices].

Aim: To demonstrate the efficacy of endoscopic ligation in treatment and prevention of bleeding from esophageal varices in patients with liver cirrhosis and portal hypertension.

Material And Methods: We performed a retrospective analysis of 338 patients with liver cirrhosis who underwent ligation for the period 2009 - May 2016. There were 209 (61.

[Endoscopic transpapillary interventions in diagnostics and treatment of patients with diseases of the pancreatobiliary area].

It was performed analysis of efficiency of endoscopic retrograde transpapillary interventions in diagnostics and treatment of 1513 patients with diseases of the pancreatobiliary area for the period 2008--2012. About half of patients had choledocholithiasis. There were tumors in 9.

[Indications and surgical results of chronic colostasis treatment].

Aim: To define the surgical indications in patients with chronic colostasis who were operated using original technique and to access obtained results.

Material And Methods: It was analyzed the results of surgical treatment of 81 patients with chronic colostasis in remote postoperative period. We have proved that extended left-sided hemicolectomy with rectosigmoid resection, positive mesentery root rotation and transposition of right large bowel to left part of abdominal cavity, creation of new ligamentary apparatus provide favourable remote results and increase life's quality of operated patients.

[The method of duodenal bulb plasty in case of complicated chronic ulcer of back wall of the duodenal bulb].

It was proposed the method of organ-preserving surgical treatment of chronic ulcers of back wall of duodenal bulb complicated by decompensated stenosis and penetration in intrapancreatic part of common bile duct (RF patent number 2476164 from 27.02.2013).

[Indications for surgical treatment of hard scarring gastric ulcers].

It was done the comparative analysis of the morphofunctional state of the upper gastrointestinal tract between 350 patients with effective conservative treatment and 104 patients with hard scarring gastric ulcers. The analysis identified the predictors of ineffective medical treatment and led to deliver the indications for timely surgical treatment. It was identified the next indications for planned organ-preserving surgical treatment of patients with hard scarring gastric ulcers: penetrating and non-healing ulcers with large or gigantic size in case of the adequate medical therapy, high-grade dysplasia and colonic metaplasia of the gastric epithelium in the borders or fundus of the ulcer,ulcers combination with fixed cardio-fundal or fundo-corporal hiatal hernias; hypotonic-hypokinetic type of the gastric and duodenal activity with the development of gastrostasis and pronounced duodenogastric reflux.

[Results of the study of motor and evacuation function of the stomach after gastroplasty].

The Aim Of The Study: Investigation of motor and evacuated functions of upper parts of digestive tract in patients with hard scarring gastric ulcers (HSGU) after organ-preserving surgery by gastroplasty method.

Methods And Materials: Motor and evacuated functions of the operated stomach were studied in 74 patients after gastroplasty (GP) with invaginated corporo-antral anastomosis (CAA) and 30 patients after GP with corporo-antral sphincter (KAS) formation from the ileal loop in different post-operated periods. The roentgenologic barium passage trough the upper parts of digestive tract and inter-digestive motor activity were assessed.

[Colonoscopy in the diagosis and treatment of the colon polypoid formations].

Aim Of The Study: the estimation of endoscopic methods efficacy in diagnostics and treatment of colon polypoid neoplasm. The study was carried out in versatile city hospital.

Methods And Materials: 5811 colonoscopies (CS) were executed in endoscopic department of versatile city hospital Nr.

[The peculiarities of esophageal epithelium of the vertebrates in phylogenesis and Barrett's esophagus].

The esophageal epithelium of vertebrates was studied in phylogenetic aspect and in patients with Barrett's esophagus (BE). The comparative investigation was undertaken to detect phylogenetic recapitulations in the course of BE development. The complex of histochemical methods for selective demonstration of mucins and proteins was used.

[Azygoportal disconnection at esophageal varicose veins dilatation].

Two original organ-saving surgical technologies are suggested for surgical prophylaxis of bleedings from esophageal and gastric varicose veins dilatation. The azygoportal disconnection surgery has been performed at 42 patients. The rate of bleeding recurrences was 4.

Comparative pre- and postoperative results analysis of functional state of the esophagus assessment in patients with various stages of achalasia.

Objective: The aim of this study was to evaluate main results of morpho-functional state of the esophagus assessment in patients with various stages of achalasia before and after surgical treatment.

Methods: Between 1993 and 2002, a total of 65 patients with achalasia (26 males, 39 females; mean age 44.5+/-14.

[Surgical treatment of bleedings from varicose veins of the esophagus and stomach].

Experience in surgical treatment of bleedings from varicose veins of the esophagus and stomach is analyzed. Two new methods of azygo-portal separation are offered, indications and contraindications, main principles of treatment before and after surgery, short- and long-term results are described.

[Twenty-year experience of retrosternal total coloesophagoplasty with areflux anastomosis].

20-year experience of total two-stage esophagoplasty with a flap made of a left half of the colon in 57 patients with burni strictures, the second stage was anastomosis between the transplant and the esophagus. Original cologastral are flux anastomosis created in the zone of air bubble (then zone of anastomosis was invaginated in fundus of stomach) was used. Long-term results were studied in 15-20 year follow-up.