Publications by authors named "Dupuis H"

Context: Erectile dysfunction (ED) is a common sexual disorder. In France, recent evidence-based guidelines are lacking.

Aim: To provide practice guidelines on ED therapeutic management.

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Purpose: This study was performed to assess the risk factors for artificial urinary sphincter (AUS) explantation in a large multicenter cohort.

Methods: We retrospectively reviewed the medical records for all 1,233 implantations of the AMS-800 AUS device in male nonneurological patients from 2005 to 2020 across 13 French centers. Patients with neurological conditions were excluded from the study.

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  • Enhanced recovery after surgery (ERAS) is a protocol aimed at improving surgical outcomes, with evidence lacking for certain urological procedures like nephrectomy and radical prostatectomy.
  • A study was conducted at an academic institution to analyze the effects of ERAS implementation on patients undergoing these surgeries, focusing on metrics like length of stay and postoperative outcomes.
  • Results showed that patients in the ERAS group had a significantly shorter hospital stay—1.3 days less for nephrectomies and 2.2 days less for prostatectomies—without an increase in complications or readmissions.
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  • * These conditions can arise in people without obesity, may have genetic links, and usually differ from lipodystrophy syndromes, which involve areas of fat loss.
  • * The review discusses various forms of lipomatosis, including isolated conditions like Madelung disease and syndromic forms associated with genetic disorders, and highlights their potential impact on health and appearance.
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Nighttime organ transplantation aims to decrease cold ischemia duration, yet conflicting data exists on its impact on graft function and perioperative complications. This multicenter TRANSPLANT'AFUF study including 2,854 patients, transplanted between 1 January 2011, and 31 December 2022, investigated nighttime kidney transplantation's impact (8:00 p.m.

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Introduction: Artificial urinary sphincter (AUS) is the standard treatment for severe stress urinary incontinence in men. While the perineal access is considered the gold standard, some authors have proposed penoscrotal AUS in order to facilitate the procedure. The main objective of our study was to evaluate the duration of survival without revision surgery (SSRC) according to the surgical approach for primary implantation.

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  • The updated clinical practice guidelines aim to improve the first-line management of infertility in couples by revisiting existing recommendations based on recent research.
  • A systematic review was conducted by expert working groups on five major themes, resulting in 28 PICO-formulated questions addressing both male and female infertility assessments, environmental factors, ovulation induction, and reproductive surgery techniques.
  • Key recommendations include tailored fertility evaluations based on the woman's age, specific tests for both partners, and the dismissal of certain outdated procedures, with an emphasis on evidence-based approaches to optimize infertility treatment.
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Do single women and single men differ in their experiences of "singlism"? This mixed-methods research examined whether single women and single men report quantitative differences in amounts of singlehood-based discrimination and explored qualitative reports of stereotypic traits associated with single women and single men. We recruited Canadian and American single adults across two Prolific studies (total 286). The results demonstrated that single female and male participants did not differ in their personal discrimination, but female participants perceived single women to experience more discrimination than single men.

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Background: Artificial urinary sphincter (AUS) is a gold standard treatment in male stress urinary incontinence but remains poorly used in elderly patients.

Objective: To assess the efficacy, safety, and reoperation-free survival of AUS implantation in male patients over 75 yr of age.

Design Setting And Participants: We retrospectively reviewed the charts of all 1233 non-neurological male AUS implantations between 2005 and 2020 at 13 French centers.

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  • This study investigates the prevalence of endocrine tumors and related conditions in patients with neurofibromatosis type 1 (NF1) through systematic screening of 108 patients.
  • The results showed that 22.2% of patients had pheochromocytomas, with a smaller percentage presenting with gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and gastrointestinal stromal tumors (GISTs).
  • The findings suggest that pheochromocytomas are more common in NF1 patients than previously thought, highlighting the importance of regular screening, particularly for young women.
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Introduction: The COVID-19 pandemic disrupted all routine health care services in 2020. To date, data regarding adjustment and coverage of surgical backlog in the post-COVID era actually remains scarce. The aim of this study was to compare the number of urological procedures coded between 2019 and 2021 in public and private institutions to (i) quantify the variation in surgical activity linked to the shutdown in 2020 and (ii) study the adjustment of procedures over the year 2021.

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Introduction: Multidisciplinary team meetings (MTMs) in the field of pelvic floor diseases in women tend to generalize, as they are required as mandatory before mid-urethral sling implantation or sacrocolpopexy by recent decrees published by the French health authorities. However, access to these meetings is variable in the French territory. The goal of the present study was to describe the existence and the settings of these kinds of meetings in France.

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  • Immune checkpoint inhibitors (ICI) are effective in treating certain cancers but can lead to hormonal side effects, especially affecting the thyroid, resulting in conditions like hyperthyroidism and hypothyroidism.
  • A case study of a 72-year-old man illustrates how ICI therapy for metastatic melanoma led to an initial worsening of hyperthyroidism due to a toxic nodule, followed by persistent hypothyroidism requiring long-term treatment, with ultrasound revealing significant thyroid changes.
  • The case suggests that while the evolution of thyroid conditions under ICI therapy is not well-documented, pre-existing toxic nodules are not a reason to avoid ICI treatment, as long as patients are monitored closely.
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The past decade has seen the emergence of numerous alternatives to traditional surgery for benign prostatic obstruction. Further trials are ongoing and will probably change our views on management of male lower urinary tract symptoms.

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Background: With an increasing prevalence in industrialized countries, lithiasis represents a public health problem with significant economic cost. Ureteroscopy is nowadays the main treatment for kidney and ureteral stones with increasingly broad indications. While this treatment is relatively safe and effective, the complications can be severe.

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Introduction: Urinary incontinence after High Intensity Focused ultrasound (HIFU) is a poorly documented issue. To our knowledge, no study has evaluated the outcomes of artificial urinary sphincter (AUS) after HIFU. The aim of this study was to evaluate the functional outcomes of AUS for post-HIFU urinary incontinence.

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Aims: To evaluate the impact of an history of radiation therapy on the outcomes of artificial urinary sphincter (AUS) implantation in male patients.

Methods: The charts of all patients who underwent AUS implantation for stress urinary incontinence (SUI) after prostate surgery in thirteen centers between 2004 and 2020 were retrospectively reviewed. We excluded patients with neurogenic SUI.

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Background: Artificial urinary sphincter (AUS) is the gold standard for the management of moderate to severe stress urinary incontinence (SUI) in the male population. While outcomes of this device in postprostatectomy incontinence (PPI) are widely described, those obtained for incontinence after benign prostatic obstruction (BPO) surgery remains poorly explored.

Objective: To compare continence outcomes after AUS implantation in a PPI population with those obtained in men incontinent after BPO surgery.

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Purpose Of Review: Stress urinary incontinence (SUI) is mostly seen after prostate surgery (radical prostatectomy or benign prostatic obstruction [BPO] relief). As new surgical techniques (laser, endoscopic enucleation) have been dramatically expanded in the past decade, a focus on postoperative SUI is necessary to provide the best management in this iatrogenic situation.

Recent Findings: Surgery is the main option for curative management of SUI after BPO as no oral medication is recommended.

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Background: immunotherapy became the first line treatment of metastatic renal cell carcinoma (mRCC). Nevertheless, a better understanding of the specificities of targeted therapies (TT) in the elderly population could be helpful in order to improve the management of mRCC in this population. The aim of this retrospective study was to assess efficacy and safety of sunitinib and sorafenib used as first-line TT in 70 years older patients compared to younger patients.

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Purpose: To compare transcorporal vs bulbar artificial urinary sphincter (AUS) implantation in men with fragile urethra and to investigate the risk factors of AUS explantation in this population.

Methods: The charts of all male patients who had an AUS implantation between 2004 and 2020 in 16 centers were reviewed retrospectively. The primary endpoint was device explantation-free survival.

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Purpose: The main objective of this study was to assess the prevalence and risk factors of male artificial urinary sphincter (AUS) mechanical failures and nonmechanical failures.

Materials And Methods: The charts of all male patients who underwent AUS implantation between 2004 and 2020 in 16 centers were retrospectively reviewed. Patients with neurogenic stress urinary incontinence (SUI) were excluded as well as revisions/explantations due to infections and/or erosions.

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Introduction: Evaluation of fetal well-being during labor is based on fetal heart rate (FHR) analysis, which requires physiology expertise. The aim of the present study was to assess medical residents' fetal physiology training in terms of theoretical knowledge, FHR interpretation, and use of second-line examinations.

Methods: This single-center, prospective study of obstetrics and gynecology residents (N = 34) at CHU de Lille Hospital (Lille, France) was conducted from November 2017 to November 2018.

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Phakomatoses encompass a group of rare genetic diseases, such as von Hippel-Lindau syndrome (VHL), neurofibromatosis type 1 (NF1), tuberous sclerosis complex (TSC) and Cowden syndrome (CS). These disorders are due to molecular abnormalities on the RAS-PI3K-Akt-mTOR pathway for NF1, TSC and CS, and to hypoxia sensing for VHL. Phakomatoses share some phenotypic traits such as neurological, ophthalmological and cutaneous features.

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