Publications by authors named "Dupraz Chrystelle"
Children and adolescents who are being treated or have been treated for acute leukemia have a secondary immunodeficiency linked to chemotherapy, resulting in an increased risk of infections. Some of which can be prevented by vaccination but its effectiveness is not optimal during chemotherapy. Upon cessation of chemotherapy, the time required for immune reconstitution varies from three months to more than a year, depending on lymphocyte subpopulations, the patient's age, and the intensity of the treatment received.
View Article and Find Full Text PDFBackground: ECIL-2021 recommends discontinuing empirical antibiotic therapy (EAT) in febrile-neutropenic children after 72 h of treatment and at least 24-48 h of apyrexia in the case of fever of unknown origin (FUO). These guidelines are rarely applied to high-risk children's neutropenia.
Material And Methods: We retrospectively included all consecutive FUO episodes occurring during profound neutropenia ≥ 10 days in children in our institution.
Article Synopsis
- - A 13-year-old immunocompromised patient with febrile neutropenia due to osteosarcoma developed a catheter-associated bloodstream infection caused by a Gram-positive bacillus previously not linked to infections in children.
- - The bacterial species was identified using Sanger sequencing and was found to be multi-susceptible, especially to amoxicillin, leading to a treatment plan involving piperacillin/tazobactam for seven days.
- - Despite phylogenetic analyses revealing the complexity of the genus, they did not effectively predict the patient's clinical outcome based solely on 16S rDNA sequence information.
Introduction: The professional situation of patients treated for childhood cancer differs from country to country. The aim of the study is to study, with the French sociocultural specificities, the first professional integration of these young people.
Methods: A sequential quantitative-qualitative mixed approach associates 16 individual interviews and responses to a self-questionnaire of 254 young cancer survivors (sex-ratio=1, median age 23.